"Yeah, it's a lot," Gailey told reporters as his team prepares for Sunday's game. "That puts a lot of stress on your defense to prepare for that week in and week out. He's done a good job of running what they've put in and done a good job of keeping it varied so it's not the same all the time."
The 49ers unleashed their latest offensive threat in Sunday's 34-0 drubbing of the New York Jets. Kaepernick ran for 50 yards on five attempts.
Gailey said the Bills would probably use backup quarterback Tyler Thigpen in practice this week to simulate Kaepernick. Thigpen ran 113 times for 656 yards and four touchdowns during his senior year with Coastal Carolina, in 2006.
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