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Rookie Bryce Brown filled in nicely for McCoy, running for 347 yards and four touchdowns in his first two career starts. But Brown had just 40 yards in the next two games and fumbled four times in four games.
Coach Andy Reid said Brown will rotate in with McCoy.
The Eagles (4-10) are trying to play spoiler against the Redskins (8-6), who are in a three-way tie for first in the NFC East.