| Transactions |
| Date | Player | POS | Transaction |
|---|
| June 12, 2017 | King Dunlap | T | retired |
| June 11, 2017 | Melvin Ingram | DE | re-signed, Four-year extension (through 2021) |
| June 2, 2017 | Dan Feeney | G | signed/draft choice, Four-year contract (through 2020) |
| June 2, 2017 | Mike Lee | CB | cut |
| May 17, 2017 | Rayshawn Jenkins | SAF | signed/draft choice, Four-year contract (through 2020) |
| May 17, 2017 | Toby Baker | P | signed |
| May 16, 2017 | Carlos Fields | LB | cut |
| May 15, 2017 | Orlando Franklin | G | cut |
| May 15, 2017 | Tre Boston | DB | signed, One-year contract (through 2017) |
| May 11, 2017 | Forrest Lamp | G | signed/draft choice, Four-year contract (through 2020) |
| May 11, 2017 | Isaac Rochell | DT | signed/draft choice, Four-year contract (through 2020) |
| May 11, 2017 | Mike Williams | WR | signed/draft choice, Four-year contract (fifth-year option) |
| May 11, 2017 | Sam Tevi | T | signed/draft choice, Four-year contract (through 2020) |
| May 11, 2017 | Zamir Carlis | DT | cut |
| May 8, 2017 | Aaron Taylor | | signed |
| May 2, 2017 | Tre Boston | DB | cut |
| May 1, 2017 | Artavis Scott | WR | signed |
| May 1, 2017 | Austin Ekeler | RB | signed |
| May 1, 2017 | Jake McGee | TE | cut |
| May 1, 2017 | Jason Verrett | CB | team exercises option, Fifth-year option on rookie contract |
| Apr 25, 2017 | Dontrelle Inman | WR | re-signed/rest FA |
| Apr 12, 2017 | Jeff Cumberland | TE | re-signed/unrest FA, One-year contract (through 2017) |
| Apr 3, 2017 | Andre Williams | RB | re-signed/excl. FA, One-year tender (through 2017) |
| Apr 3, 2017 | Isaiah Burse | WR | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 30, 2017 | Sean McGrath | TE | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 23, 2017 | Branden Oliver | RB | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 22, 2017 | Adrian Phillips | SS | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 21, 2017 | Kenjon Barner | RB | signed/unrest FA, One-year contract (through 2017) |
| Mar 20, 2017 | Geremy Davis | WR | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 20, 2017 | Tenny Palepoi | DE | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 18, 2017 | Kenny Wiggins | G | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 14, 2017 | Brock Hekking | LB | cut |
| Mar 13, 2017 | Asante Cleveland | TE | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 13, 2017 | King Dunlap | T | cut |
| Mar 10, 2017 | Damion Square | NT | re-signed/unrest FA, Two-year contract (through 2018) |
| Mar 9, 2017 | Russell Okung | T | Declared Free Agent |
| Mar 9, 2017 | Branden Oliver | RB | Declared Free Agent |
| Mar 9, 2017 | Damion Square | NT | Declared Free Agent |
| Mar 9, 2017 | Dexter McCluster | WR | Declared Free Agent |
| Mar 9, 2017 | Dontrelle Inman | WR | Restricted Free Agent |
| Mar 9, 2017 | Jahleel Addae | SS | re-signed/unrest FA, Four-year contract (through 2020) |
| Mar 9, 2017 | Jahleel Addae | SS | Declared Free Agent |
| Mar 9, 2017 | Jeff Cumberland | TE | Declared Free Agent |
| Mar 9, 2017 | Kellen Clemens | QB | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 9, 2017 | Kellen Clemens | QB | Declared Free Agent |
| Mar 9, 2017 | Kenny Wiggins | G | Declared Free Agent |
| Mar 9, 2017 | Korey Toomer | ILB | Restricted Free Agent |
| Mar 9, 2017 | Mike Windt | LS | re-signed/unrest FA, Four-year extension (through 2020) |
| Mar 9, 2017 | Mike Windt | LS | Declared Free Agent |
| Mar 9, 2017 | Ronnie Hillman | RB | Declared Free Agent |
| Mar 9, 2017 | Russell Okung | T | signed/unrest FA, Four-year contract (through 2020) |
| Mar 9, 2017 | Sean Lissemore | NT | Declared Free Agent |
| Mar 9, 2017 | Tenny Palepoi | DE | Declared Free Agent |
| Mar 9, 2017 | Kenjon Barner | RB | Declared Free Agent |
| Mar 7, 2017 | Brandon Flowers | CB | cut |
| Mar 7, 2017 | Steve Johnson | WR | cut |
| Feb 27, 2017 | Melvin Ingram | DE | Designated franchise player, non-exclusive franchise tag |
