| Transactions |
| Date | Player | POS | Transaction |
|---|
| June 8, 2017 | Mitch Mathews | WR | signed |
| May 30, 2017 | Mitch Mathews | WR | cut |
| May 25, 2017 | Charles Harris | DE | signed/draft choice, Four-year contract (fifth-year option) |
| May 16, 2017 | Davon Godchaux | DT | signed/draft choice, Four-year contract (through 2020) |
| May 5, 2017 | Cameron Malveaux | DE | signed |
| May 5, 2017 | Chase Allen | LB | signed |
| May 5, 2017 | Cordrea Tankersley | CB | signed/draft choice, Four-year contract (through 2020) |
| May 5, 2017 | Damore'ea Stringfellow | WR | signed |
| May 5, 2017 | De'Veon Smith | RB | signed |
| May 5, 2017 | Drew Morgan | WR | signed |
| May 5, 2017 | Eric Smith | T | signed |
| May 5, 2017 | Francis Owusu | WR | signed |
| May 5, 2017 | Isaac Asiata | G | signed/draft choice, Four-year contract (through 2020) |
| May 5, 2017 | Isaiah Ford | WR | signed/draft choice, Four-year contract (through 2020) |
| May 5, 2017 | Joby Saint Fleur | DE | signed |
| May 5, 2017 | Larry Hope | DB | signed |
| May 5, 2017 | Malcolm Lewis | WR | signed |
| May 5, 2017 | Matt Haack | P | signed |
| May 5, 2017 | Maurice Smith | DB | signed |
| May 5, 2017 | Praise Martin-Oguike | DE | signed |
| May 5, 2017 | Raekwon McMillan | LB | signed/draft choice, Four-year contract (through 2020) |
| May 5, 2017 | Torry McTyer | DB | signed |
| May 5, 2017 | Vincent Taylor | DT | signed/draft choice, Four-year contract (through 2020) |
| May 1, 2017 | Ja'Wuan James | T | team exercises option, Fifth-year option on rookie contract |
| Apr 17, 2017 | Anthony Steen | C | re-signed/excl. FA, One-year tender (through 2017) |
| Apr 17, 2017 | Michael Thomas | FS | re-signed/rest FA, One-year tender (through 2017) |
| Apr 17, 2017 | Mike Hull | LB | re-signed/excl. FA, One-year tender (through 2017) |
| Apr 5, 2017 | David Fales | QB | signed/unrest FA, One-year contract (through 2017) |
| Mar 31, 2017 | T.J. McDonald | DB | signed/unrest FA, One-year contract (through 2017) |
| Mar 30, 2017 | Mitch Mathews | WR | signed, One-year contract (through 2017) |
| Mar 29, 2017 | T.J. McDonald | DB | suspended, 8 games (NFL Substance Abuse Policy) |
| Mar 22, 2017 | Avery Young | T | signed, Three-year contract (through 2019) |
| Mar 22, 2017 | Daniel Davie | DB | cut |
| Mar 21, 2017 | Kiko Alonso | MLB | re-signed/rest FA, Four-year contract (through 2020) |
| Mar 16, 2017 | Jermon Bushrod | G | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 10, 2017 | Isa Abdul-Quddus | SS | cut |
| Mar 10, 2017 | Jordan Cameron | TE | retired |
| Mar 10, 2017 | Lawrence Timmons | LB | signed/unrest FA, Two-year contract (through 2018) |
| Mar 10, 2017 | Nate Allen | DB | signed/unrest FA, One-year contract (through 2017) |
| Mar 10, 2017 | Ted Larsen | G | signed/unrest FA, Three-year contract (through 2019) |
| Mar 10, 2017 | William Hayes | DE | traded, w/ draft pick for 2017 6th-round pick |
| Mar 9, 2017 | David Fales | QB | Declared Free Agent |
| Mar 9, 2017 | Ted Larsen | G | Declared Free Agent |
| Mar 9, 2017 | T.J. McDonald | DB | Declared Free Agent |
| Mar 9, 2017 | Andre Branch | DE | re-signed/unrest FA, Three-year contract (through 2019) |
| Mar 9, 2017 | Andre Branch | DE | Declared Free Agent |
| Mar 9, 2017 | Anthony Fasano | TE | signed/unrest FA, One-year contract (through 2017) |
| Mar 9, 2017 | Bacarri Rambo | FS | Declared Free Agent |
| Mar 9, 2017 | Chimdi Chekwa | DB | Declared Free Agent |
| Mar 9, 2017 | Damien Williams | RB | Restricted Free Agent |
| Mar 9, 2017 | Dominique Jones | TE | Declared Free Agent |
| Mar 9, 2017 | Donald Butler | OLB | Declared Free Agent |
| Mar 9, 2017 | Jermon Bushrod | G | Declared Free Agent |
| Mar 9, 2017 | John Denney | LS | Declared Free Agent |
| Mar 9, 2017 | John Denney | LS | re-signed/unrest FA, One-year contract (through 2017) |
| Mar 9, 2017 | Jordan Cameron | TE | Declared Free Agent |
| Mar 9, 2017 | Julius Thomas | TE | traded, for 2017 7th-round pick |
| Mar 9, 2017 | Kenny Stills | WR | re-signed/unrest FA, Four-year contract (through 2020) |
| Mar 9, 2017 | Kenny Stills | WR | Declared Free Agent |
| Mar 9, 2017 | Kiko Alonso | MLB | Restricted Free Agent |
| Mar 9, 2017 | Michael Thomas | FS | Restricted Free Agent |
| Mar 9, 2017 | Reshad Jones | FS | re-signed, Five-year extension (through 2021) |
| Mar 9, 2017 | Nate Allen | DB | Declared Free Agent |
| Mar 9, 2017 | Lawrence Timmons | LB | Declared Free Agent |
| Mar 9, 2017 | Anthony Fasano | TE | Declared Free Agent |
| Mar 8, 2017 | Lafayette Pitts | DB | re-signed/excl. FA, One-year tender (through 2017) |
| Mar 8, 2017 | Thomas Duarte | TE | re-signed/excl. FA, One-year tender (through 2017) |
| Feb 27, 2017 | Avery Young | T | cut |
| Feb 16, 2017 | Ifo Ekpre-Olomu | CB | cut |
| Feb 16, 2017 | Mario Williams | DE | cut |
