In their first home appearance since a Game 6 win over the Carolina Hurricanes in the Stanley Cup Finals, the Oilers took advantage of a two-man power play when Shawn Horcoff dished the puck to Smyth for an easy tap in past Panthers backup goalie Craig Anderson.
The Western Conference champion Oilers improved to 2-0 in the preseason while the Panthers fell to 0-2 on their Alberta road trip.
The Oilers scored first when a pair of highly touted prospects connected on the power play. Rob Schremp found defenseman Tom Gilbert at the point for a shot past new Panthers starter Alex Auld.
Florida tied it late in the first period with a power-play goal. Panthers defenseman Martin Lojek beat goalie Dwayne Roloson, who made his first start since sustaining a season-ending knee injury in Game 1 of the Stanley Cup Finals.
Roloson didn't show any ill effects from his offseason knee operation. Early in the second period, the 36-year-old goalie was sharp in holding off the Panthers during a full two-minute, two-man advantage.
He made 15 saves on 16 shots before being replaced by Jussi Markkanen halfway through the game.
Markkanen also made big saves in the third period to preserve the win as Florida had another long two-man advantage, their fifth of the night.