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Roddick has not re-entered himself back into the ITF's anti-doping system following his retirement.
Novak Djokovic, Roger Federer, and Victoria Azarenka all easily advanced to the second round of the US Open Tuesday.
Defending champion Andy Murray is one of six past champs in the men's field at the U.S. Open, which will begin Aug. 26.
There were no major upsets on Saturday as Serena Williams, Novak Djokovic and David Ferrer all advanced to the fourth round.
Numerous injuries could significantly alter the Wimbledon championship landscape on both the men's and women's side.
Two tennis superstars, Roger Federer and Rafael Nadal, could be facing each other a little sooner than usual at Wimbledon.

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