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Despite building a rivalry that has turned ugly at times, Tyson Fury and Deontay Wilder have maintained a level of respect for the other's prowess in the boxing ring. The accomplished heavyweights will give the division its first championship trilogy in nearly 30 years Saturday when they meet in the main event of a Las Vegas boxing card with Fury's WBC belt on the line. The pay-per-view portion of the event is set for 9 p.m. ET from T-Mobile Arena in Las Vegas. 

The latest Fury vs. Wilder III odds from Caesars Sportsbook list Fury as the -280 favorite (risk $280 to win $100) to win, while Wilder is the +230 underdog. The duration of the fight and method of victory are a couple of the Fury vs. Wilder prop bets to consider as well. Before making any Fury vs. Wilder III picks or bets, make sure you check out the boxing predictions and betting advice from SportsLine combat analyst Brandon Wise

Wise, who is the combat sports editor for CBS Sports, is an experienced boxing analyst. His strong 2021 boxing record includes correctly calling victories for social-media-star-turned-boxing-phenom Jake Paul over former UFC fighters Ben Askren and Tyron Woodley. Moreover, the respected combat analyst also called Jamel Herring (+105) to defeat Carl Frampton (-125) for the WBO junior lightweight title in April. Anyone who has followed Wise's combat sports picks has seen massive returns. 

Now, with Saturday's fight fast approaching, Wise has studied Fury vs. Wilder 3 from every angle and identified the best value in the Wilder vs. Fury props. You can check out his confident prop picks and his money-line selection at SportsLine

Tyson Fury vs. Deontay Wilder III preview 

In the aftermath of his loss in the rematch, Wilder memorably fired trainer Mark Breland because Breland threw in the towel to signal the referee to stop the fight. Many observers viewed the move as a pride-driven and hasty dismissal of an accomplished trainer and former WBA welterweight champion, but Wilder has insisted the changes he has made in his camp are for the better.

Wilder hired a new chief trainer in Malik Scott, a former opponent who Wilder knocked out in the first round of their March 2014 fight. Scott retired from fighting following a lopsided loss to Luis Ortiz in 2016 and his position with Wilder's team marks his first as a professional trainer. Wilder retained well-regarded trainer Jay Deas and cut man Don House, who also has worked with several UFC fighters.

In order to get proper sparring from an opponent with a similar build to Fury, Wilder brought in 6-foot-7 heavyweight Robert Helenius, a former European boxing champion who has been in the ring with some of the sport's top names. Helenius notably knocked out top-10 contender Adam Kownacki in March of last year and will fight a rematch with him on the undercard of Saturday's main event. 

How to make Tyson Fury vs. Deontay Wilder 3 picks

We'll reveal that Wise likes the under 7.5 rounds. He's also locked in on a prop that returns around 9-1. You can only see his expert boxing picks and analysis at SportsLine

Who wins Tyson Fury vs. Deontay Wilder III? And which prop bet brings a huge return? Visit SportsLine now to see Brandon Wise's best bets for Saturday, all from the CBS combat sports specialist who has crushed his boxing picks in 2021, and find out.