An American Athletic battle is on tap between the Cincinnati Bearcats and the South Florida Bulls at 7 p.m. ET Tuesday at Yuengling Center. South Florida is 13-16 overall and 9-6 at home, while Cincinnati is 18-10 overall and 4-6 on the road. Cincinnati has struggled mightily against the spread with a 10-18 record against the number. Meanwhile, USF has actually been solid against the spread with a 16-12 record against the number.

And while Cincinnati has won each of the last 10 head-to-head meetings, South Florida is actually 7-3 against the spread during that span. The Bearcats are favored by 4 points in the latest South Florida vs. Cincinnati odds, while the over-under is set at 127. Before entering any Cincinnati vs. South Florida picks, you'll want to see the college basketball predictions from the model at SportsLine.

This model, which simulates every game 10,000 times, has crushed its top-rated college basketball picks against the spread the past three years, returning $2,770 to $100 players. It also entered Week 18 of the 2019-20 season on a 72-48 run on all top-rated college basketball picks. Anybody who followed it has seen huge returns.

Now, the model has set its sights on South Florida vs. Cincinnati. You can head to SportsLine to see its picks. Here are several college basketball odds for South Florida vs. Cincinnati:

  • South Florida vs. Cincinnati spread: South Florida +4
  • South Florida vs. Cincinnati over-under: 127 points
  • South Florida vs. Cincinnati money line: South Florida +157, Cincinnati -184

What you need to know about South Florida

The Bulls didn't have too much breathing room in their game with the Temple Owls on Sunday, but they still walked away with a 64-58 win. Four players on South Florida scored in the double digits: guard Justin Brown (13), forward Michael Durr (12), guard David Collins (11), and forward Antun Maricevic (10).

What you need to know about Cincinnati

The matchup between the Bearcats and the Houston Cougars on Sunday was not a total blowout, but with the Bearcats falling 68-55 on the road, it was darn close to turning into one. A silver lining for Cincinnati was the play of forward Tre Scott, who dropped a double-double on 17 points and 11 rebounds.

A pair of defensive numbers to keep in mind before tip-off: South Florida comes into the contest boasting the 13th-fewest points allowed per game in college basketball at 62.2. As for Cincinnati, they have been holding their opponents to a field goal percentage of 39.80%, which places them 20th in college basketball. We'll find out if either of these strengths ends up making the difference in the matchup.

How to make South Florida vs. Cincinnati picks

The model has simulated South Florida vs. Cincinnati 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Cincinnati vs. South Florida? And which side of the spread cashes in over 50 percent of simulations? Visit SportsLine now to see which side of the spread you need to jump on Tuesday, all from the model that has crushed its college basketball picks, and find out.