The two top-ranked teams in the nation clash on Tuesday night in the 2021 Good Sam Empire Classic when No. 2 UCLA plays No. 1 Gonzaga. Both squads roll into this matchup on five-game win streaks with their eyes set on extending it to six in an early-season NCAA Tournament resume builder. In the last game for each side, the Bruins defeated Bellarmine 75-62, while the Bulldogs overpowered Central Michigan en route to a 107-54 victory. This is a rematch from the 2021 Final Four, a game Gonzaga won 93-90 on a 3-point buzzer beater.

Tipoff is at 10 p.m. ET from T-Mobile Arena in Las Vegas. Caesars Sportsbook lists the Bulldogs as seven-point favorites in the latest Gonzaga vs. UCLA odds. The over-under for total points is set at 156. Before locking in any UCLA vs. Gonzaga picks, be sure to see the college basketball predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $2,100 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on UCLA vs. Gonzaga and revealed its coveted picks and predictions. You can head to SportsLine now to see all of the model's college basketball picks. Here are several college basketball odds and betting lines for Gonzaga vs. UCLA:

  • UCLA vs. Gonzaga spread: Gonzaga -7
  • UCLA vs. Gonzaga over-under: 156 points 
  • UCLA vs. Gonzaga money line: UCLA +240, Gonzaga -300
  • GONZ: Bulldogs are 4-0 ATS in their last four games following a straight-up win of more than 20 points 
  • UCLA: Bruins are 6-0 ATS in their last six games as an underdog
Featured Game | Gonzaga Bulldogs vs. UCLA Bruins

Why Gonzaga can cover

The Bulldogs have a versatile group and there are four players who average at least 10 points per game. Freshman Chet Holmgren has played well through his first five collegiate games. The five-star recruit is third on the team in points (12.8), first in rebounds (6.8), first in blocks (3.4), and first in field-goal percentage (70.6).

Holmgren stuffed the stat sheet in the season opener against Dixie State. He finished with 14 points, 13 rebounds, six assists with seven blocks. In the rout against Central Michigan, Holmgren tallied a season-high 19 points, while grabbing five boards. He shot 7 of 9 from the field and knocked down two 3-pointers. He's been a nice addition to a roster that returned players such as Drew Timme (18.8 ppg), Julian Strawther (14.8 ppg) and Andrew Nembhard (7.0 ppg) from last year's Final Four squad. 

Why UCLA can cover

The Bruins have three players who average at least 15 points per game. They are led by junior guard Johnny Juzang who is averaging a team-high 19.8 points per game. Juzang has logged back-to-back 25 point performances against No. 7 Villanova and Long Beach State. Junior Jaime Jaquez Jr. is second on the team with 15.6 points while snagging a team-high 7.6 rebounds per game. Jaquez Jr. has scored at least 14 points in four consecutive games. His best game this season came against No. 7 Villanova. The California native recorded a double-double and finished with 21 points, 13 rebounds with three assists. 

Rounding out this trio for the Bruins is senior guard Jules Bernard. He averages 15.4 points, 4.8 boards, and three assists per game. Bernard opened the season with four straight games with at least 15 points. The senior guard had a solid outing against Long Beach State. He finished a season-high 22 points, five rebounds while dishing out seven assists. Bernard also shot an efficient 8 of 11 from the field and 4 of 5 from beyond the arc. 

How to make UCLA vs. Gonzaga picks

SportsLine's model is leaning over on the point total, projecting the teams to combine for 160 points. The model also says one side of the spread hits in over 70 percent of simulations. You can only see the model's Gonzaga vs. UCLA picks at SportsLine.

So who wins UCLA vs. Gonzaga? And which side of the spread hits in over 70 percent of simulations? Visit SportsLine now to see which side of the spread you need to jump on, all from the model that has crushed its college basketball picks, and find out.