The second round of the ACC Tournament opens Wednesday at noon ET with a matchup between Louisville and Florida State, two teams squarely on the NCAA Tournament bubble. Vegas opened this game as a pick'em, but Florida State is now favored by one point.

Before making any kind of pick on this matchup that is virtually dead even, you need to see what SportsLine's advanced computer model has to say.

Last season, the model was an impressive 755-636-20 on A-rated picks, returning $6,529 to any $100 player who followed it. And with the NCAA Tournament just around the corner, the model is heating up, entering the ACC tourney on a strong 12-6 run on its top-rated college basketball picks.

Now, it has simulated Louisville vs. Florida State 10,000 times and its picks and projections are in.

We can tell you the computer says Phil Cofer, Florida State's second-leading scorer, goes for 11 points for the Seminoles, while Deng Adel and Quintin Snider both go for 12 points for Louisville. But will those performances be enough to lift the Cardinals to a cover or a win?

The model says one side is winning against the spread over 50 percent of the time, and you can get that pick only at SportsLine.

The model has taken into account Louisville's struggles late in the season. The Cardinals, once a virtual lock for the NCAA Tournament, dropped four of five to conclude the regular season.

They enter play Wednesday as one of the first four teams out of the NCAA Tournament, according to CBS Sports bracketology expert Jerry Palm, and a loss to the Seminoles could be catastrophic for their at-large bid hopes.

But just because Louisville (19-12) is desperate for a win doesn't mean that the Cardinals will be able to pull out the victory.

Florida State (20-10) is projected as a No. 9 seed by Palm and also needs a strong showing this week to solidify its tournament status after losing two of three down the stretch.

The Seminoles beat Louisville 80-76 on the road in early February and will again look to use a high-flying offense that averages 82 points to get a victory on Wednesday that would all but wrap up a spot in the Big Dance.

So which side of Louisville-Florida State do you need to be all over? Visit SportsLine now to see  the point-spread pick that hits over 50 percent of the time, all from the model that has crushed its college basketball picks.