A Big East battle is on tap between the Marquette Golden Eagles and the No. 5 Villanova Wildcats at 9 p.m. ET on Wednesday at Finneran Pavilion. The Wildcats are 12-2 overall and 5-0 at home, while Marquette is 9-10 overall and 3-3 on the road. Villanova has won 10 of its last 11 games, while Marquette has lost four of its last five. 

The Wildcats are favored by 11-points in the latest Villanova vs. Marquette odds from William Hill Sportsbook, and the over-under is set at 138.5. Before entering any Marquette vs. Villanova picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Villanova vs. Marquette. You can head to SportsLine to see its picks. Here are several college basketball odds for Villanova vs. Marquette:

  • Villanova vs. Marquette spread: Villanova -11
  • Villanova vs. Marquette over-under: 138.5 points
Latest Odds: Villanova Wildcats -11

What you need to know about Villanova

Villanova was able to grind out a solid win over the Georgetown Hoyas on Sunday, winning 84-74. Villanova's forward Jermaine Samuels was one of the most active players for the squad, shooting 6-for-7 from downtown and finishing with 32 points, five dimes and six rebounds. Samuels is averaging 10.9 points, 6.6 rebounds and 2.2 assists per game this season. 

The Wildcats have dominated this series over the years. In fact, Villanova is 15-3 in its last 18 meetings against Marquette. The Wildcats are also 8-0 in their last eight games at home against the Golden Eagles. 

What you need to know about Marquette

Meanwhile, it was close but no cigar for the Golden Eagles as they fell 71-68 to the Creighton Bluejays this past Saturday. Guard D.J. Carton (16 points) and forward Jamal Cain (14 points) were the top scorers for Marquette. The Golden Eagles feature three players averaging over 12 points per game, including Carton, who leads the team in scoring at 12.7 points per contest. 

Marquette is in the midst of a down season and the Golden Eagles have struggled to cover the spread. Marquette is 2-10 against the spread in its last 12 games and the Golden Eagles are just 1-8 ATS in their last nine games on the road. 

How to make Marquette vs. Villanova picks

The model has simulated Villanova vs. Marquette 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Villanova vs. Marquette? And which side of the spread hits in over 50 percent of simulations? Visit SportsLine now to see which side of the spread to jump on Wednesday, all from the proven computer model that has crushed its college basketball picks.