NCAA Basketball: Ohio State at Kentucky
Stephen R. Sylvanie / USA TODAY Sports

The Michigan State Spartans and the No. 4 Ohio State Buckeyes will face off in a Big Ten battle at 9 p.m. ET on Thursday at Jack Breslin Student Events Center. Michigan State is 12-9 overall and 9-3 at home, while the Buckeyes are 18-5 overall and 7-3 on the road. Michigan State has dominated this series over the years, winning seven of its last 10 meetings against Ohio State. 

The Buckeyes are favored by four-points in the latest Michigan State vs. Ohio State odds from William Hill Sportsbook, and the over-under is set at 145.5. Before entering any Ohio State vs. Michigan State picks, you'll want to see the college basketball predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,500 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Michigan State vs. Ohio State. You can head to SportsLine to see its picks. Here are several college basketball odds for Michigan State vs. Ohio State:

  • Michigan State vs. Ohio State spread: Michigan State +4
  • Michigan State vs. Ohio State over-under: 145.5 points

What you need to know about Michigan State

Michigan State was able to grind out a solid victory over the Illinois Fighting Illini on Tuesday, winning 81-72. Guard Joshua Langford and forward Aaron Henry were among the main playmakers for MSU as the former dropped a double-double with 16 rebounds and 13 points, and the latter had 20 points and five assists in addition to six boards.

Henry leads the Spartans in scoring, averaging 15.2 points per game. The junior forward has scored 20 or more points in each of his last two outings, and he recorded 10 points, seven rebounds and three assists in Michigan State's 79-62 defeat against Ohio State earlier this season. 

What you need to know about Ohio State

Meanwhile, Ohio State was within striking distance but couldn't close the gap on Sunday as the Buckeyes fell 92-87 to the Michigan Wolverines. Despite the defeat, Ohio State got a solid performance out of guard Duane Washington Jr., who shot 5-for-10 from beyond the arc and finished with 30 points. For the season, Washington Jr. is averaging 15.6 points, 2.9 assists and 2.8 rebounds per game. 

Ohio State has won 10 of its last 12 games and the Buckeyes are 6-0 against the spread in their last six road games. However, Ohio State is 4-10 against the spread in its last 14 meetings with the Spartans. 

How to make Michigan State vs. Ohio State picks

The model has simulated Michigan State vs. Ohio State 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Ohio State vs. Michigan State? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine right now to see which side of the Michigan State vs. Ohio State spread you need to jump on, all from the computer model that has crushed its college basketball picks.

Latest Odds: Michigan State Spartans +4