The Stanford Cardinal and the Southern California Trojans will face off in a Pac-12 clash at 5 p.m. ET on Thursday at Maples Pavilion. Stanford is 8-5 overall and 3-0 at home, while USC is 11-3 overall and 2-1 on the road. 

The Trojans are favored by five points in the latest Stanford vs. USC odds from William Hill Sportsbook, and the over-under is set at 138.  Before entering any USC vs. Stanford picks, you'll want to see the college basketball predictions from the model at SportsLine.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of over $2,300 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Stanford vs. Southern Cal. You can head to SportsLine to see its picks. Here are several college basketball odds for Southern Cal vs. Stanford:

  • Stanford vs. Southern California spread: Stanford +5
  • Stanford vs. Southern California over-under: 138 points

What you need to know about Stanford

The Cardinal lost to the Colorado Buffaloes on Saturday, 77-64. Oscar da Silva posted a double-double on 22 points and 12 rebounds. It was the second consecutive loss for Stanford. Colorado used a 14-0 run to take a 40-26 lead at the half. The Cardinal never got closer than eight points in the second half. Ziaire Williams added 13 points. 

Stanford has been holding opponents to a field goal percentage of 39.1, which is 26th in college basketball. This season, da Silva is leading the Cardinal in scoring at 19.3 points per game and also is best on the team in  rebounds at 7.3 per game. Stanford has won its last five home games vs, USC. 

What you need to know about Southern California

Meanwhile, USC lost a tight one on Tuesday, 58-56 to the Oregon State Beavers. Evan Mobley dropped a double-double on 13 boards and 12 points. It was his sixth double-double of the season. The loss snapped a six-game winning streak for the Trojans. Southern California went scoreless in the final 2:19 of the game. 

The Trojans have been holding their opponents to a field goal percentage of 37.4, which is fifth in the nation. Southern California has 81 blocks for an average of 5.8 blocks per game, eighth best in the nation. USC is now 78-5 in its last 83 games when holding opponents to fewer than 70 points. 

How to make Stanford vs. Southern California picks

The model has simulated Stanford vs. Southern California 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You can only see the pick at SportsLine.

So who wins USC vs, Stanford? And which side of the spread hits in almost 60 percent of simulations? Visit SportsLine now to see which side of the USC vs. Stanford spread to jump on Thursday