Jay Wright and the Villanova Wildcats aim for another Big East Tournament crown on Saturday evening. After a semifinal win over UConn on Friday, Villanova faces the Creighton Bluejays in the 2022 Big East Tournament final at Madison Square Garden in New York. The Wildcats are 25-7 overall this season with a mark of 18-4 in Big East play and nine wins in the last 10 games. Creighton is 22-10 overall and 14-7 in conference games.

Caesars Sportsbook lists the Wildcats as seven-point favorites for this 6:30 p.m. ET tipoff. The total number of points Vegas thinks will be scored, or the over-under, is 128.5 in the latest Creighton vs. Villanova odds. Before finalizing any Villanova vs. Creighton picks, be sure to check out the college basketball predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Creighton vs. Villanova and revealed its coveted picks and predictions. You can head to SportsLine to see all of the model's college basketball picks. Here are several college basketball odds and trends for Villanova vs. Creighton:

  • Creighton vs. Villanova spread: Villanova -7
  • Creighton vs. Villanova over-under: 128.5 points
  • Creighton vs. Villanova money line: Villanova -300, Creighton +240
  • CRE: The Bluejays are 12-7-2 against the spread in conference games
  • NOVA: The Wildcats are 11-9-2 against the spread in conference games
Featured Game | Villanova Wildcats vs. Creighton Bluejays

Why Creighton can cover

Creighton's offense is balanced and effective. Four players average in double-figures for the Bluejays, and Creighton is No. 3 in the Big East in 2-point accuracy. Creighton is converting more than 51 percent of 2-point shots in conference play, and Villanova has a weakness in rim protection. The Wildcats are second-worst in the Big East with a block rate of only 8.7 percent. On the other end, Creighton is dominant, leading the conference in adjusted defensive efficiency. 

The Bluejays lead the Big East in shooting efficiency allowed, headlined by opponents shooting only 43.5 percent on 2-point shots. That ranks in the top 10 nationally, and Creighton is No. 4 in the country in free-throw rate allowed. Villanova lands outside the top 200 of the country in assist percentage, and Creighton is holding opponents to just 31.3 percent from 3-point range in Big East play.

Why Villanova can cover

Villanova is known for its offense, but the Wildcats are No. 2 in the Big East in defensive efficiency. Villanova is No. 3 in the conference in turnover rate, forcing a giveaway on 18.4 percent of possessions, and the Wildcats are also near the top of the Big East in defensive rebound rate, free-throw rate allowed and 3-point defense. Creighton is just No. 9 in the Big East in adjusted offensive efficiency, and the Bluejays are last in the conference in turnover rate. 

On the other end, Villanova is hyper-efficient, leading the Big East in offensive efficiency. No team in the nation has a higher free- throw percentage (82.7 percent) than Villanova, and the Wildcats rank in the top three of the Big East in turnover rate, live-ball turnover rate, 2-point shooting, 3-point shooting and free-throw creation rate. Creighton is also quite passive on defense, ranking No. 9 or worse in the Big East in steal rate, block rate and turnover creation rate.

How to make Creighton vs. Villanova picks

SportsLine's model is leaning over on the total, projecting the teams to combine for 140 points. The model also says one side of the spread hits more than 50 percent of the time. You can only see the model's pick at SportsLine.

So who wins Villanova vs. Creighton? And which side of the spread hits more than 50 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college basketball picks, and find out.