The Arizona Wildcats held an early lead in each of their last two games, only to squander it en route to losses. They scored the first 13 points against Colorado last week but went on to suffer their 11th consecutive defeat dating back to last season, a 24-13 home setback. The Wildcats hope to end the slide when they host the Arizona State Sun Devils in the 2020 season finale for both Pac-12 teams on Friday. Kickoff from Arizona Stadium in Tucson is scheduled for 7 p.m. ET.

Arizona (0-4) has lost three straight meetings with the Sun Devils, including a 24-14 defeat in the 2019 regular-season finale. Arizona State (0-2) also gave up a lead on Saturday, allowing a touchdown with 1:09 remaining in the fourth quarter of a 25-18 home setback against UCLA. The Sun Devils are 10-point favorites in the latest Arizona State vs. Arizona odds from William Hill Sportsbook, while the over-under for total points scored is 55. Before making any Arizona vs. Arizona State picks, check out the college football predictions from SportsLine's Zack Cimini.

Cimini is a highly respected Las Vegas handicapper who's never afraid to buck conventional wisdom. He also has an uncanny feel for the tendencies of the Wildcats, going an incredible 9-1 in his last 10 college football picks involving Arizona. Anyone who has followed him is way up.

Now, Cimini has set his sights on Arizona State vs. Arizona. You can visit SportsLine now to see the picks. Here are the college football odds and trends for Arizona vs. Arizona State:

  • Arizona State vs. Arizona spread: Sun Devils -10
  • Arizona State vs. Arizona over-under: 55 points
  • Arizona State vs. Arizona money line: Sun Devils -380, Wildcats +300
  • ASU: The Sun Devils are 1-9 against the spread in their last 10 games as favorites
  • AZ: The Wildcats are 2-9 ATS in their last 11 conference games
Latest Odds: Arizona Wildcats +12

Why Arizona State can cover

The Sun Devils easily could be 2-0 this season, as they squandered leads over the final two minutes in both of their games. They've been stellar to start the second half, however, keeping their opponents scoreless in the third quarter. Arizona State has generated 45 quarterback pressures while registering eight sacks and 17 tackles for loss this season.

Jayden Daniels completed 21-of-35 attempts for 225 yards with a touchdown against UCLA while also running for a score. The sophomore quarterback was picked off in the second half, ending his streak of 203 consecutive attempts without an interception. Daniels has gained 117 yards on the ground this year and is 28 away from reaching 500 for his career.

Why Arizona can cover

The Wildcats hope for another strong effort on the ground in the 94th Duel in the Desert after racking up 268 rushing yards against Colorado. Sophomore Michael Wiley ran seven times for 122 yards and senior Gary Brightwell gained 117 on 22 carries, marking the third time Arizona has had a pair of 100-yard rushers in a game in the last three seasons. Wiley amassed 106 yards on 31 rushes in 10 contests as a freshman.

Wide receiver Jamarye Joiner made only two catches for 22 yards on Saturday but is hoping for a performance similar to the one he had against Arizona State last year. The redshirt sophomore had the best game of his collegiate career versus the Sun Devils, hauling in seven passes for 140 yards and a pair of touchdowns. Senior linebacker Anthony Pandy made two interceptions in last week's loss after recording just one in 27 games over his first three seasons.

How to make Arizona State vs. Arizona picks

Cimini is leaning over the total, and he's also found a critical X-factor that makes one side of the spread a must-back. You can only get the pick at SportsLine

So who wins Arizona State vs. Arizona? And what crucial X-factor causes one side of the spread to hit hard? Visit SportsLine now to see which side of Arizona vs. Arizona State you need to jump all over Friday, all from the expert who is 9-1 in his last 10 picks involving the Wildcats.