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The Arizona State Sun Devils (2-0) will take on the BYU Cougars (2-0) on Saturday, September, 18 at 10:15 p.m. ET at LaVell Edwards Stadium in Provo, Utah. BYU is 2-0 overall and 1-0 at home, and is coming off a huge win over in-state rival Utah. ASU is 2-0 overall and have yet to play a road game in 2021. 

The Sun Devils are favored by 3.5 points in the latest BYU vs. Arizona State odds from Caesars Sportsbook, and the over-under for total points scored is set at 51. Before entering any Arizona State vs. BYU picks, you'll want to check out the college football predictions and analysis from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on BYU vs. Arizona State and just revealed its picks and predictions. You can head to SportsLine now to see its picks. Here are several college football odds and betting trends for BYU vs. Arizona State:

  • BYU vs. Arizona State spread: BYU +3.5
  • BYU vs. Arizona State over-under: 51 points
  • BYU vs. Arizona State moneyline: Arizona State -170, BYU +145
Featured Game | BYU Cougars vs. Arizona State Sun Devils

What you need to know about BYU

BYU was able to grind out a solid win over Utah on Saturday, winning 26-17. Cougars quarterback Jaren Hall turned in an exceptional performance against the Utes, throwing for 150 yards and three touchdowns, and rushing for 92 yards.

BYU's 2021 offense hasn't been as explosive as they were in 2020, but they still have plenty of talent on that side of the ball to be competitive in every game on their schedule. Defensively, the Cougars are allowing an average of 383 yards per game, which could be problematic against Arizona State's prolific offense. 

What you need to know about Arizona State

The Sun Devils blew out UNLV 37-10 behind an outstanding defensive performance and another standout outing from quarterback Jayden Daniels, who threw for 175 yards and two touchdowns, in addition to picking up 125 yards on the ground.

The difference in this matchup could prove to be ASU's stout defensive line, who racked up five sacks against UNLV and held the Rebels to 88 total yards on the ground. 

How to make Arizona State vs. BYU picks

The model has simulated BYU vs. Arizona State 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the model's BYU vs. Arizona State pick at SportsLine.

So who wins Arizona State vs. BYU? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks, and find out.