Best 2018 College football bowl upset picks: Iowa State knocks off Washington State in Alamo Bowl

With unfamiliar teams battling injuries and suspensions, players opting out of games, and a variety of weather conditions in late December, oddsmakers don't always get it right during bowl season. And with the 2018-19 college bowl schedule finalized and lines out for every game, there's plenty of value to be had if you know where to look. Before you lock in any selections this bowl season, be sure to check out which underdogs SportsLine's proven computer model is backing. These college football upset picks could lead to huge payouts on the money line for anybody bold enough to take them. 

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen massive returns. Over the past three years, this proprietary computer model has generated a jaw-dropping $4,210 profit for $100 bettors on its top-rated point-spread picks. 

The model made some huge calls on Championship Week, including nailing Ohio State (-16.5) against Northwestern and Oklahoma (-9.5) against Texas. It was also all over big upsets during the 2018 season such as Ohio State (+4.5) beating Michigan on Rivalry Week. And when it comes to all top-rated picks, the model has been red-hot, entering the 2018 college football bowl season on a blistering 45-25 run. Anybody who has followed it is way, way up. 

Now, it has simulated every 2018 college football bowl game 10,000 times. One of the top 2018 bowl upset picks from the model we'll give away: No. 25 Iowa State (+155) knocks off No. 12 Washington State in the 2018 Alamo Bowl on Dec. 28. 

The Cyclones won seven of their last eight to finish up the season. And they're no strangers to pulling off upsets since that stretch included a road victory over Oklahoma State (-10) and a win over a favored West Virginia (-4.5) squad. 

The model has identified the Alamo Bowl 2018 as a possible letdown spot for Washington State after the Cougars fell to rival Washington in the final week of the regular season, ending their chances of a Pac-12 crown and any discussion of making a run for the College Football Playoff. Confidently back the Cyclones in this matchup because they win outright in well over half of simulations.

But for its top upset pick of bowl season, the model has identified an underdog of greater than six points that is poised to stun college football. This pick would pay out over +200 on the money line, and anyone who backs it could have a holiday season for the ages.

So what favorites are going down during the college football bowl season? And which massive underdog could lead to a huge payout? Visit SportsLine now to see which underdogs shock college football this postseason, all from the model that nailed Ohio State's upset of Michigan this year.

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