Conference USA teams will try to earn their first conference win of the season on Friday when the Charlotte 49ers host the Middle Tennessee Blue Raiders at Jerry Richardson Stadium in Charlotte, N.C. The game will be televised on CBS Sports Network. The 49ers (2-1) have yet to play a conference game. They own nonconference wins this season against Duke and Gardner-Webb but lost last week at Georgia State. The victory over the Blue Devils was the program's first against a Power Five program. Meanwhile the Blue Raiders (1-2, 0-1 in Conference USA) dropped their conference opener last week at UTSA

Kickoff between Charlotte and Middle Tennessee is 6:30 p.m. ET. The 49ers are three-point favorites in the latest Charlotte vs. MTSU odds from Caesars Sportsbook, while the over-under for total points scored is 56. Before finalizing any MTSU vs. Charlotte picks make sure you see the college football predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Charlotte vs. MTSU. You can visit SportsLine now to see the picks. Here are the college football odds and trends for MTSU vs. Charlotte:

  • Charlotte vs. Middle Tennessee spread: 49ers -3
  • Charlotte vs. Middle Tennessee Under: 56 points
  • Charlotte vs. Middle Tennessee money line: 49ers -145, Blue Raiders +125
  • CLT: WR Grant DuBose ranks second in Conference USA in yards per reception (27.3).
  • MT: The Blue Raiders lead the conference in turnover margin per game (2.0).
Featured Game | Charlotte 49ers vs. Middle Tenn. Blue Raiders

Why Charlotte can cover

Charlotte has a dual-threat quarterback in Chris Reynolds. A former walk-on from Mocksville, N.C., the 5-foot-11 senior is 42-of-75 passing for 585 yards with five touchdowns and two interceptions this season. He also has rushed for 111 yards on 22 carries with two touchdowns.

In addition, Reynolds has two dangerous targets in Grant DuBose and Victor Tucker. The two have combined for 24 receptions, 386 yards and two touchdowns this season. In the season-opening upset of Duke, both DuBose and Tucker had 100-yard receiving games.

Why MTSU can cover

Even though he will be making his first career start, quarterback Chase Cunningham has shown he can be productive. A 5-foot-11 junior from Knoxville, Tenn., Cunningham is 19-for-30 passing for 259 yards, three touchdowns and no interceptions this season. He has led five touchdown drives in the last 12 possessions he has started.

In addition, defensive end Jordan Ferguson has been a disruptive force to start this season. A 6-foot-2 junior from Atlanta, Ferguson leads the team and ranks second in Conference USA with five tackles for loss. He also has two sacks, seven hurries, a forced fumble and a fumble recovery.

How to make MTSU vs. Charlotte picks

SportsLine's model is leaning under on the total, projecting the teams to combine for 50 points. The model also says one side of the spread hits in 60 percent of simulations. You can only get the pick at SportsLine

So who wins Charlotte vs. MTSU? And which side of the spread hits in 60 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.