Update: This game has been postponed due to COVID-19

Trevor Lawrence's absence due to COVID-19 could end up costing him the Heisman Trophy in what could be his final season with the Clemson Tigers. It also played a part in ending fourth-ranked Clemson's regular-season winning streak at 39 games, as it fell at Notre Dame in double overtime last time out. Lawrence will attempt to get the Tigers back on track as he returns for their ACC matchup against the host Florida State Seminoles on Saturday. Kickoff from Bobby Bowden Field at Doak Campbell Stadium in Tallahassee is set for noon ET. Clemson (7-1, 6-1 ACC) trails 20-13 in the all-time series but has dominated of late, winning five straight meetings -- the last two by 49 and 31 points, respectively. 

The Seminoles (2-6, 1-6) suffered a 38-22 setback at North Carolina State last Saturday, marking the fifth time this season they've allowed more than 37 points. The Tigers are 35.5-point favorites in the latest Clemson vs. Florida State odds from William Hill Sportsbook, while the over-under for total points scored is 64.5. Before making any Florida State vs. Clemson picks, check out the college football predictions from SportsLine's Emory Hunt, given the success he's had picking games involving the Seminoles. 

The founder of Football Gameplan, Hunt played running back at the University of Louisiana-Lafayette and coached high-school football before becoming a SportsLine expert and CBS Sports HQ analyst. He enjoyed a dominant 2019 season, going 116-79 against the spread while returning nearly $3,000 to $100 bettors.

Moreover, Hunt has a keen eye for the Seminoles' tendencies. He's a stunning 14-5 against the spread in his last 19 college football picks for or against FSU.

Now, Hunt has set his sights on Clemson vs. FSU. You can visit SportsLine now to see the picks. Here are the college football odds from William Hill and trends for FSU vs. Clemson:

  • Clemson vs. Florida State spread: Tigers -35.5
  • Clemson vs. Florida State over-under: 64.5 points
  • Clemson vs. Florida State money line: Tigers -80000, Seminoles +4000
  • CLEM: The Tigers are 11-3 against the spread in their last 14 games as road favorites
  • FSU: The Seminoles are 1-6 ATS in their last seven home contests

Why Clemson can cover

Lawrence, who can tie the school record of 32 career wins by a starting quarterback on Saturday, has thrown touchdown passes to nine different players this season -- including five to Amari Rodgers. The senior is the Tigers' top wideout, leading the team in catches (48), receiving yards (720) and TD catches (six). Rodgers posted his second 100-yard performance of 2020 in the Nov. 7 loss at Notre Dame, hauling in eight passes for 134 yards.

Another of Lawrence's top targets is senior wide receiver Cornell Powell, who racked up 161 yards and a TD against the Fighting Irish. Sophomore tight end Davis Allen has caught a scoring pass in four of his last five contests while Travis Etienne is second on the team with 37 receptions and 491 yards. The senior running back has gained 634 yards on 121 carries while running for 10 touchdowns, with nine coming during his current six-game streak.

Why Florida State can cover

The Seminoles will have Jordan Travis back under center as freshman Chubba Purdy, who made his first career start last Saturday, underwent season-ending collarbone surgery this week. Travis started Florida State's previous four contests before getting hurt and helped lead the team to a 31-28 upset victory over then-No. 5 North Carolina. The sophomore threw for one touchdown and ran for two others against the Tar Heels as the Seminoles held on after leading 31-7 at halftime.

Travis has completed 59-of-113 attempts for 864 yards with four TDs and five interceptions this season. He'll likely be looking often in the direction of Ontaria Wilson, who leads Florida State in catches (28) and receiving yards (332) while tying for first with a pair of touchdown receptions. The junior wideout hauled in seven passes for 117 yards and a TD against North Carolina State.

How to make Clemson vs. Florida State picks

Hunt is leaning over on the total, and he's also found a critical x-factor that makes one side of the spread a must-back. You can only get the pick at SportsLine

So who wins Florida State vs. Clemson? And which critical x-factor has Hunt jumping all over one side of the spread? Visit SportsLine now to see which side of the Clemson vs. Florida State spread to jump on Saturday, all from the expert who is 14-5 on spread picks involving the Seminoles, and find out.