National title contenders will get some big tests during the Week 3 college football schedule. No. 1 Alabama is -14.5 in the Week 3 college football odds at Caesars Sportsbook as it travels to The Swamp for the 3:30 p.m. ET SEC on CBS game against No. 11 Florida. No. 10 Penn State, meanwhile, gets a visit from No. 22 Auburn in a game where the Nittany Lions are laying five points.

The Week 3 college football lines indicate some potential blowouts coming for other contenders. No. 3 Oklahomaa is -22.5 against Nebraska, No. 6 Clemson is -28 against Georgia Tech and No. 2 Georgia is -31.5 against South Carolina. Which college football spreads have the most value? Before locking in any college football bets, be sure to see the top Week 3 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider -- a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread -- and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past two-plus years, he is 84-59 in his popular best bets column at SportsLine, including going a profitable 5-4 to start the 2021 season. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 3 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 3 college football expert predictions

One of Sallee's top college football picks for Week 3: He's going over 52 in the ACC matchup between Clemson and Georgia Tech on Saturday at 2:30 p.m. ET. 

The Tigers have hit the 52 mark or higher the past two years by themselves when playing the Yellow Jackets. Clemson won 73-7 last year and 52-14 in 2019. It also picked up a 49-21 victory over Georgia Tech in 2018.

Several of the key faces have changed for Clemson, but the Tigers still have big offensive upside. Sallee sees this as a great tune-up game for tougher ACC opponents on the horizon, and is expecting another offensive explosion from Dabo Swinney's squad.

"The Tigers offense needs to develop their identity, and a game against a Yellow Jackets team that is wildly undermanned is the perfect chance to do so," Sallee told SportsLine. "This has 60-burger written all over it."

Featured Game | Clemson Tigers vs. Georgia Tech Yellow Jackets

How to make Week 3 college football picks 

Sallee has also found two other college football picks he's high on, including a must-see play in a big game where he says the favorite could surpass the spread by halftime. You can only see his picks at SportsLine.

What are the best bets for Week 3 of college football? And which favorite runs away and covers with ease? Visit SportsLine now to see Barrett Sallee's college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.