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LSU and Oklahoma went down in surprising upsets last week. Contenders are looking to avoid the same fate as the Week 5 college football schedule continues on Saturday. The Week 5 college football odds from William Hill list Alabama as a 17.5-point favorite against Texas A&M in the 3:30 p.m. ET SEC on CBS matchup. Texas survived a shootout against Texas Tech last week and is listed as an 11.5-point home favorite against TCU in Week 5.

After a week off, Clemson is -28 against Virginia, while Georgia is laying 6.5 points at home against Auburn. Which Week 5 college football bets should you make on those games and others? Before locking anything in for this weekend's action, be sure to see the top Week 5 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider -- a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread -- and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way, posting a winning record in his weekly college football best bets column since that point. 

He went 59-35-2 (63 percent, plus $2,037) on all his college football picks for SportsLine in 2019, and he also enters Week 5 of the 2020 college football season on a 48-26 streak on his best bets since the start of last year. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 5 college football odds from William Hill and is sharing his top three best bets over at SportsLine. Get his top college football picks now

Top Week 5 college football expert predictions

One of Sallee's top college football picks for Week 5: He's backing Oklahoma (-7) to pick up the win and cover as the Sooners travel to Iowa State for a 7:30 p.m. ET kickoff on Saturday.

For the second consecutive year, Kansas State stunned Oklahoma when the Wildcats erased a three-score deficit and pulled off the 38-35 upset last week. Sallee has plenty of concerns about Oklahoma's defense, but he's also considered that the Sooners have put up massive offensive numbers through two games.

Iowa State, meanwhile, has struggled at times on offense. The Cyclones mustered just two scores in their 31-14 loss against Louisiana on Sept. 12. And though they ultimately picked up the win, the Cyclones converted only 3 of 11 third downs against TCU last week.

Sallee sees great value in laying only one touchdown in this matchup, warning bettors to "not buy into the trap" of being too down on Oklahoma after last week. 

How to make Week 5 college football picks 

Sallee has also found two other college football picks he's high on, including a strong play on an underdog he believes can win outright. You can only see who he's backing at SportsLine.

What are the best bets for Week 5 of college football? And which underdog should you be all over? Visit SportsLine now to see Barrett Sallee's college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.