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No. 5 Ohio State has been rolling since losing to Oregon in its second game of the season. The Buckeyes have won all five of their games since then by at least three touchdowns. They'll face another test on Saturday when they host No. 20 Penn State as part of the Week 9 college football schedule. Ohio State is a 19.5-point favorite in the latest Week 9 college football odds at Caesars Sportsbook.

Elsewhere in the country, No. 6 Michigan is set to face No. 8 Michigan State (+4) and No. 10 Ole Miss will travel to No. 18 Auburn (-3). Which Week 9 college football lines should you be targeting in your bets? Before making any Week 9 college football picks on those games or others, be sure to see the latest college football predictions and betting advice from SportsLine's proven model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,900 for $100 players on its top-rated college football picks against the spread. It also enters Week 9 of the 2021 season on a 26-11 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 9 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top Week 9 college football predictions

One of the top college football picks the model is recommending for Week 9: No. 12 Kentucky (+1.5) covers at Mississippi State in a 7 p.m. ET matchup on Saturday. The model projects Kentucky to win outright by several points, bringing plenty of value on the Wildcats as small road favorites. Kentucky has proven to be worth your money this year, as the Wildcats are 6-0 against the spread.

Of course, that streak has to come to an end at some point. But with a sturdy defense and a rested team following a bye week, SportsLine's model isn't predicting it'll be this week. In the simulations, the model has Kentucky covering the spread well over 60 percent of the time, while the point total (47) goes under almost 70 percent of the time, so those are both smart picks for straight bets or a potential parlay. 

Another one of the college football predictions from the model: No. 25 BYU (-2.5) covers against Virginia in a late 10:15 p.m. ET start in Provo. The Cougars have already knocked off a pair of ranked teams this season, taking down Utah and Arizona State. They are coming off a win at Washington State in Week 8. Running back Tyler Allgeier rushed for 191 yards and two touchdowns in the win over Washington State.

Allgeier ranks seventh in the FBS in rushing yards (861) and is tied for sixth in rushing touchdowns (11). SportsLine's model is expecting him to rush for nearly 100 yards and a touchdown against Virginia, a team led by former BYU coach Bronco Mendenhall. The Cougars are covering the spread in well over 60 percent of simulations, while the under (66) is hitting over 60 percent of the time. 

How to make Week 9 college football picks 

The model has also made the call on who wins and covers in every other game on the Week 9 college football schedule, and it's calling for a top-10 team to go down hard. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which top-10 squad goes down hard? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,900 in profit over the past five-plus seasons, and find out.

Week 9 college football odds (via Caesars)

Here are the college football lines for some of Week 9's most notable matchups:

Saturday, Oct. 30

Michigan vs. Michigan State (4, 51.5)

Featured Game | Michigan State Spartans vs. Michigan Wolverines

Pittsburgh vs. Miami (FL) (+11, 62)

Featured Game | Pittsburgh Panthers vs. Miami (FL) Hurricanes

Baylor vs. Texas (+2.5, 62)

Featured Game | Baylor Bears vs. Texas Longhorns

Cincinnati  vs. Tulane (+24.5, 62.5)

Featured Game | Tulane Green Wave vs. Cincinnati Bearcats

Iowa vs. Wisconsin (-3, 37)

Featured Game | Wisconsin Badgers vs. Iowa Hawkeyes

Iowa State vs. West Virginia (+7, 47.5)

Featured Game | West Virginia Mountaineers vs. Iowa State Cyclones

Georgia vs. Florida (+14.5, 50.5)

Featured Game | Florida Gators vs. Georgia Bulldogs

Texas Tech vs. Oklahoma (-17.5, 68)

Featured Game | Oklahoma Sooners vs. Texas Tech Red Raiders

Colorado vs. Oregon (-24.5, 49)

Featured Game | Oregon Ducks vs. Colorado Buffaloes

Duke vs. Wake Forest (-16.5, 69)

Featured Game | Wake Forest Demon Deacons vs. Duke Blue Devils

Ole Miss vs. Auburn (-2, 66)

Featured Game | Auburn Tigers vs. Ole Miss Rebels

SMU vs. Houston (-1, 62.5)

Featured Game | Houston Cougars vs. SMU Mustangs

Kentucky vs. Mississippi State (pick, 47)

Featured Game | Mississippi State Bulldogs vs. Kentucky Wildcats

Kansas vs. Oklahoma State (-30.5, 56)

Featured Game | Oklahoma State Cowboys vs. Kansas Jayhawks

Penn State vs. Ohio State (-17.5, 59.5)

Featured Game | Ohio State Buckeyes vs. Penn State Nittany Lions

UNC vs. Notre Dame (-3.5, 62.5)

Featured Game | Notre Dame Fighting Irish vs. North Carolina Tar Heels

BYU vs. Virginia (+2.5, 63.5)

Featured Game | BYU Cougars vs. Virginia Cavaliers

Fresno State vs. San Diego State (-1, 46.5)

Featured Game | San Diego State Aztecs vs. Fresno State Bulldogs