No. 13 Wisconsin has a chance to do to No. 3 Ohio State what Illinois did last week. Wisconsin fell out of the College Football Playoff picture after losing to the unranked Fighting Illini, and the unbeaten Buckeyes would face an uphill climb back into contention should Wisconsin upset them. The Badgers are 14.5-point underdogs in the latest college football odds, one of the largest college football spreads of the week involving a ranked team. Wisconsin vs. Ohio State is one of five Big Ten games involving ranked teams on Saturday. Unbeaten Penn State puts its No. 6 ranking on the line when the Nittany Lions visit Michigan State. James Franklin and company are favored by almost a touchdown, according to the current college football lines. No. 17 Minnesota (-16.5) takes on visiting Maryland, No. 20 Iowa (-10) heads to Northwestern, and No. 19 Michigan hosts No. 8 Notre Dame in Ann Arbor. Notre Dame vs. Michigan is a pick'em, which means neither team is favored in the latest college football odds. Before locking in any Week 9 college football picks for these matchups or any others, consult the college football predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times, and those who have followed it have seen huge returns. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,200 for $100 players on its top-rated college football picks against the spread.

The model enters Week 9 of the 2019 season on a strong run, going 92-59 on its top-rated college football picks. It also nailed Illinois (+30.5) easily staying within the spread against No. 6 Wisconsin in one of the largest upsets of the entire season in Week 8. Anybody who has been following it is way up.

One of the Week 9 college football picks the model is recommending: No. 6 Penn State (-6.5) covers on the road against Michigan State. 

The Nittany Lions picked up a huge 28-21 win over Michigan last week, keeping them undefeated and in the mix for the Big Ten title and a College Football Playoff bid. They'll have to keep style points in mind, however, with five other undefeated teams currently sitting in front of them. Michigan State, meanwhile, is just 2-5 against the spread and ranks 12th in the Big Ten in total offense. The model projects that the Spartans muster just 11 points, while Penn State quarterback Sean Clifford throws for well over 200 yards as the Nittany Lions cover in over 60 percent of simulations. 

Another one of the 2019 Week 9 college football predictions from the model: California stays within the spread as a 21.5-point road underdog when the Golden Bears face No. 12 Utah. 

Cal is 4-3 this season, but just 1-3 in the Pac-12 and riding a three-game losing streak. Quarterback Chase Garbers has thrown for 952 yards and eight touchdowns, while running back Christopher Brown Jr. has 480 rushing yards and four touchdowns. The Golden Bears have been consistent on offense all season, averaging 324 yards per game, but it's Cal's defense that will be a difference against Utah, as the Golden Bears allow just 18.7 points per game. 

The model projects that Cal holds Utah quarterback Tyler Huntley to under 200 passing yards. That helps the Golden Bears cover the spread over 70 percent of the time.

That's why the model has the Cardinal covering in well over 60 percent of simulations. Meanwhile, the over (52.5) has all the value since it hits 50 percent of the time.

The model also has made the call on every other FBS matchup in Week 9, including the monster SEC showdown between No. 2 LSU and No. 9 Auburn. It also knows a line in another game is way off, saying one side of the spread hits in almost 70 percent of simulations. You need to see its college football picks before locking in any of your own. 

So what college football picks can you make with confidence in Week 9? And which line is Vegas way off on? Check out the latest Week 9 college football odds below, and then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned over $4,200 in profit over the past four seasons.

Illinois at Purdue (-9.5, 59)
Mississippi State at Texas A&M (-10.5, 50.5)
Iowa at Northwestern (+10, 37)
Miami (Fla.) at Pittsburgh (-5.5, 43.5)
Wisconsin at Ohio State (-14.5, 49.5)
Penn State at Michigan State (+6.5, 43.5) 
Oklahoma State at Iowa State (-10.5, 63.5)
Texas at TCU (+1.5, 58.5)
Virginia at Louisville (+3.5, 52)
Auburn at LSU (-10.5, 58.5)
Maryland at Minnesota (-16.5, 58)
Duke at North Carolina (-3.5, 53.5)
South Carolina at Tennessee (+4.5, 47.5)
Arkansas at Alabama (-31.5, 55.5)
Texas Tech at Kansas (+4, 64.5)
Boston College at Clemson (-34, 59)
Missouri at Kentucky (+10.5, 45)
Notre Dame at Michigan (PK, 52)
Arizona State at UCLA (+3.5, 55.5)
California at Utah (-21.5, 37)
Washington State at Oregon (-14, 64.5)