The Tribe built leads of 6-0 and 12-7 but couldn't make them hold up. Receiver Earnest Edwards threw a 19-yard scoring pass to Jaquan Blair to give Maine (3-5, 1-3 Colonial Athletic Association) a 7-6 lead. Later, Fagnano threw a 67-yard score to Edwards for a 14-12 lead Maine would never surrender.
Joe Fitzpatrick's 1-yard run with 6:12 remaining before halftime made it 21-12. Then, on the second play of the second half, Fagnano threw a 64-yard TD pass to Blair for a 16-point lead. Blair caught four passes for 115 yards.
Hollis Mathis rushed 52 yards and scored three times for the Tribe (2-6, 0-4), but he struggled throwing the ball and completed just 4 of 22 pass attempts for 68 yards.
Owen Wright led William & Mary on the ground with 73 yards rushing on 13 carries.
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