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The Maryland Terrapins have not won their first two conference games in a season since joining the Big Ten in 2014. They haven't defeated a top-five opponent since edging then-No. 5 Florida State 20-17 on Oct. 30, 2004. The Terrapins look to end both droughts when they host the fifth-ranked Iowa Hawkeyes for a Big Ten showdown on Friday. Maryland (4-0, 1-0 Big Ten) won its first conference game of the 2021 season on Sept. 17, when it got past Illinois 20-17 on the road.

Kickoff at Maryland Stadium in College Park is set for 8 p.m. ET. The Hawkeyes are three-point favorites in the latest Iowa vs. Maryland odds from Caesars Sportsbook, while the over-under for total points scored is 47.5. Before finalizing any Maryland vs. Iowa picks or college football predictions, you need to see what the proven SportsLine Projection Model has to say.

The model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, it enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Iowa vs. Maryland and just revealed its CFB picks and predictions. You can visit SportsLine now to see all of the model's college football picks. Here are the college football odds and betting lines for Maryland vs. Iowa:

  • Iowa vs. Maryland spread: Hawkeyes -3
  • Iowa vs. Maryland over-under: 47.5 points 
  • Iowa vs. Maryland money line: Hawkeyes -160, Terrapins +140
  • IOWA: The Hawkeyes are 5-1 against the spread in their last six overall contests 
  • MD: The Terrapins are 3-8 ATS in their last 11 conference games
Featured Game | Maryland Terrapins vs. Iowa Hawkeyes

Why Iowa can cover

The Hawkeyes have done an excellent job defensively, as they are third in the nation this season with an average of 11 points allowed per game. Since posting a 31-28 victory over Nebraska on Nov. 23, 2018, Iowa has given up 24 points or fewer in 26 consecutive contests. The Hawkeyes also made opponents pay for turnovers in 2021, turning all nine of their takeaways into a total of 51 points.

Iowa leads the Big Ten and ranks 10th in the country with six interceptions. Seniors Riley Moss and Matt Hankins have made two apiece, with the former returning both of his for touchdowns in the Hawkeyes' season-opening 34-6 victory against then-No. 17 Indiana. Iowa has recorded 70 interceptions since 2017, the most by any team in the nation.

Why Maryland can cover

Taulia Tagovailoa has thrown for over 300 yards in three of the Hawkeyes' four games this season while Dontay Demus Jr. has eclipsed the century mark in receiving yards three times. Both had big games in the Terrapins' 37-16 victory over Kent State on Saturday, with Tagovailoa recording 384 passing yards and Demus amassing 108 on just four catches. The senior receiver has hauled in a pass in 26 consecutive games and had a touchdown reception in seven of his last eight contests.

Maryland leads the Big Ten and is tied for fifth in the nation with 16 sacks this season, registering at least two in each of its four games. The 16 sacks have been for a loss of 129 yards, the second-most in the country behind Pittsburgh's 132 on the same amount of sacks. A junior college transfer, senior defensive lineman Sam Okuayinonu leads the Terrapins and ranks third in the conference with four sacks in as many games this year after recording 1.5 in 16 contests over his first two seasons at Maryland.

How to make Iowa vs. Maryland picks

SportsLine's model is leaning under on the point total. In fact, it says neither Petras nor Tagovailoa throws for more than 205 yards. It also has generated an against-the-spread pick that cashes in well over 60 percent of simulations. You can only get that Iowa vs. Maryland pick at SportsLine.

So who wins Maryland vs. Iowa? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to see which side of the Iowa vs. Maryland spread to back, all from the advanced model that is up almost $3,300 on its top-rated college football spread picks, and find out.