Lawrence completed 22 of 28 passes for 390 yards with the four scoring passes giving him 20 on the season and 101 in his four years as a starter for the Toreros (5-2, 4-0).
Emilio Martinez had 115 yards and a touchdown on 15 carries, opening the scoring with a 59-yard TD burst. Michael Bandy had 129 yards - his fifth 100-yard game of the season - and a touchdown on five receptions. Tight end Dalton Kincaid had two catches for 16 yards and two touchdowns.
The big day belong to Michael Armstead, who had four receptions for 159 yards and a touchdown, which covered 97 yards - the longest passing play in school history.
Lawrence had three TD passes in the second quarter for a 35-0 lead at the half.
Will Martin had two second-half touchdown passes for the Bulldogs (3-4, 1-3), who have lost three straight and seven straight to San Diego.
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