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The Kansas State Wildcats will try to bounce back from a shocking loss in their season-opener when they hit the road on Saturday to take on the No. 3 Oklahoma Sooners at Gaylord Family -- Oklahoma Memorial Stadium in Norman, Okla. On Sept. 12 the Wildcats (0-1) entered their season opener as 14-point favorites over Arkansas State but managed just 91 rushing yards and surrendered the game-winning touchdown with less than a minute remaining to lose 35-31. On Saturday Kansas State will face an Oklahoma team that passed for 484 yards in its season-opening blowout over Missouri State. 

Kickoff is set for noon ET. William Hill pegs the Sooners as 28-point favorites in the latest Oklahoma vs. Kansas State odds, while the over-under for total points scored is 60.5. Before making any Kansas State vs. Oklahoma picks, check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,800 for $100 players on its top-rated college football picks against the spread. It is a sizzling 13-1 on top-rated picks through three weeks of the 2020 college football season, returning over $900 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Oklahoma vs. Kansas State. You can visit SportsLine now to see the picks. Here are the college football odds from William Hill and trends for Kansas State vs. Oklahoma:

  • Oklahoma vs. Kansas State spread: Sooners -28
  • Oklahoma vs. Kansas State Over-Under: 60.5 points
  • Oklahoma vs. Kansas State money line: Sooners -4000, Wildcats +1500
  • OU: QB Spencer Rattler leads the country in passing efficiency (303.3)
  • KSU: WR Chabastin Taylor ranks third in the Big 12 in receiving yards per game (98.0)

Why Oklahoma can cover

Rattler was dazzling in his debut. The redshirt freshman from Phoenix, who was a highly-touted quarterback recruit in 2019, completed 14-of-17 passes for 290 yards and four touchdowns in only one half of work and helped Oklahoma build a 41-0 halftime lead. Rattler became the first freshman quarterback in program history to throw four touchdown passes in his first start.

In addition the Sooners have been dominant at home under Lincoln Riley. Since he took over in 2017, Oklahoma is 19-1 in Norman. Its only defeat was a 38-31 decision against Iowa State on Oct. 7, 2017. The Sooners have won 17 straight at home since.

Why Kansas State can cover

K-State has an experienced and productive quarterback in Skylar Thompson. The senior from Independence, Mo., is set to make his 29th career start against the Sooners. He is one of just four quarterbacks in school history to throw for 4,000 yards and rush for 1,000 yards, but he is the only one to do so prior to entering his senior season. He ranks sixth nationally among active quarterbacks in rushing touchdowns (19) and 15th among active players with 5,706 career total offensive yards.

The Wildcats have one of the top defensive ends in the Big 12 in junior Wyatt Hubert. A first-team All-Big 12 selection last year, Hubert is tied for fourth nationally among active players in sacks per game (0.50) and ranks seventh in tackles for loss per game (0.88).

How to make Oklahoma vs. Kansas State picks

SportsLine's model is leaning over on the total as Rattler throws for well over 300 yards, while Thompson goes for almost 200. It also says one side of the spread hits in almost 70 percent of simulations. You can only get the pick at SportsLine

So who wins KSU vs. Oklahoma? And which side of the spread hits almost 70 percent of the time? Visit SportsLine now to see which side of the Oklahoma vs. KSU spread to back, all from the advanced model that is up over $3,800 on its top-rated college football spread picks, and find out.