Getty Images

The third-ranked Oklahoma Sooners will try to keep rolling when they host the West Virginia Mountaineers in a Big 12 matchup on Saturday. The Sooners (3-0) have not been overly impressive, but they have been winning, and they think they have the pieces to make a run at a playoff spot. They will try to get things dialed in against West Virginia (2-1), which has never beaten Oklahoma in conference play. Both teams come in off six-point nonconference rivalry victories last Saturday. The Sooners held off Nebraska for a 23-17 win and WVU surprised then-No. 15 Virginia Tech 23-17.

Kickoff is set for 7:30 p.m. ET in Norman, Okla. The Sooners are the 17.5-point favorites in the latest West Virginia vs. Oklahoma odds from Caesars Sportsbook, and the over-under for total points scored is set at 56.5. Before finalizing any Oklahoma vs. West Virginia picks, make sure you check out the college football predictions and betting advice from the proven SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has locked in on WVU vs. Oklahoma and just revealed its picks and predictions. You can head to SportsLine now to see the model's college football picks. Here are several college football odds and betting lines and trends for Oklahoma vs. WVU:  

  • West Virginia vs. Oklahoma: Sooners -17.5
  • West Virginia vs. Oklahoma over-under: 56.5 points 
  • West Virginia vs. Oklahoma moneyline: Mountaineers +600, Sooners -900 
  • WVU: The Mountaineers are 3-2 ATS in their last five vs. ranked teams 
  • OU: The Sooners are 6-1 ATS in their past seven conference games
Featured Game | Oklahoma Sooners vs. West Virginia Mountaineers

Why Oklahoma can cover

Oklahoma has won all eight meetings between the teams in Big 12 competition, and its offense appears to be far more potent than WVU's. It ranks sixth in the nation in scoring (46.3 per game) and has enviable balance. Sophomore quarterback Spencer Rattler is a top NFL prospect and entered the season as a Heisman candidate after throwing for more than 3,000 yards and 28 TDs as a freshman. He has 761 yards and seven TD passes through three games, and receivers Marvin Mims, Jadon Haselwood and Mario Williams are all capable playmakers.

Haselwood and Williams have 27 receptions and four TDs between them, and Mims averages 21 yards per catch. The Sooners also are set at running back, with Kennedy Brooks (210 yards, three TDs) and Eric Gray (185 yards) getting an even split of carries. Linebacker Nik Bonitto and linemen Perrion Winfrey and Isaiah Thomas have each contributed 2.5 sacks as OU has posted 13 so far, and the defense has forced seven turnovers. The Mountaineers could find it tough to pass against the pressure, and the Sooners allow just 83 yards on the ground (21st in FBS).   

Why West Virginia can cover

West Virginia is 7-4-1 against the spread in its past 12 regular-season games and is seeking a third straight win after losing its opener to still-unbeaten Maryland. Quarterback Jarret Doege threw two interceptions in that game, but he has 452 yards with five TDs and just one pick in the past two. Five Mountaineers receivers have at least 100 receiving yards, with two averaging at least 18 yards per catch, and running back Leddie Brown is one of the best in the Big 12. The senior has 265 yards and five TDs in three games after putting up 161 on the ground last week.

Sam James and Winston Wright each have 10 receptions, and James leads the team with 166 yards and three TDs. Sean Ryan and Bryce Ford-Wheaton have a combined 15 catches for 274 yards and two scores. They should be able to find space against an OU pass defense that ranks 90th in the country and yielded 289 yards to the Cornhuskers last week. The Mountaineers are scoring 39 points per game (32nd in FBS) and allowing just 17 (33rd), and the defense has 10 sacks, three by sophomore Jared Bartlett. The Sooners are 1-2 against the spread this season.    

How to make West Virginia vs. Oklahoma picks

The model model is leaning over on the total, projecting 59 combined points. It also has generated a point-spread pick that is hitting in more than 50 percent of simulations. You can only get the model's Oklahoma vs. West Virgina ATS pick at SportsLine

So who wins the West Virginia vs. Oklahoma matchup on Saturday? And which side of the spread is hitting more than 50 percent of the time? Visit SportsLine right now to see which side of the Oklahoma vs. West Virginia spread to back Saturday, all from the advanced model on a 72-58 run on its top-rated college football picks, and find out.