The No. 3 Oregon Ducks and the Stanford Cardinal will face off in a Pac-12 clash at 3:30 p.m. ET on Saturday at Stanford Stadium. Stanford is 2-2 overall and 0-1 at home, while the Ducks are 4-0 overall and 1-0 on the road. Stanford has split its first two conference games while Oregon is 1-0 in the Pac-12. These rivals have met 81 times before and the Cardinal leads the all-time series 46-34-1.

The Ducks are favored by eight points in the latest Stanford vs. Oregon odds from Caesars Sportsbook, and the over-under is set at 57.5. Before entering any Oregon vs. Stanford picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Stanford vs. Oregon. You can head to SportsLine to see its picks. Here are several college football odds for Oregon vs. Stanford:

  • Stanford vs. Oregon spread: Oregon -8
  • Stanford vs. Oregon over-under: 57.5 points
Featured Game | Stanford Cardinal vs. Oregon Ducks

What you need to know about Stanford

Stanford came up short against the UCLA Bruins last Saturday, falling 35-24. Stanford's loss came about despite a quality game from QB Tanner McKee, who passed for three TDs and 292 yards. McKee's 56-yard touchdown toss to WR Elijah Higgins in the third quarter made for one of the most memorable moments of the evening.

McKee now has a sterling 8:0 touchdown-to-interception ratio and has also helped out on the ground with two rushing touchdowns. RB Nathaniel Peat also has two rushing touchdowns while Higgins has two touchdowns through the air. But player who's found the endzone most often is WR Brycen Tremayne who has four touchdowns on just 17 receptions.

What you need to know about Oregon

Meanwhile, Oregon was hampered by 95 penalty yards against the Arizona Wildcats on Saturday, but still took its contest against Arizona by a conclusive 41-19 score. Oregon QB Anthony Brown was slinging it as he passed for three TDs and 206 yards in addition to picking up 41 yards on the ground. Near the top of the highlight reel was Brown's 63-yard TD bomb to WR Jaylon Redd in the first quarter.

Brown has also been flawless this season with seven touchdowns and no interceptions. He also has two rushing touchdowns but takes a backseat on the ground to RB CJ Verdell. He ranks third in the Pac-12 with 334 rushing yards, and has also accounted for six total touchdowns (four rushing, two receiving). Oregon is also expecting to have star edge rusher Kayvon Thibodeaux (ankle) back at full speed for this matchup after he was limited last week. 

How to make Stanford vs. Oregon picks

The model has simulated Oregon vs. Stanford 10,000 times and the results are in. The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Stanford vs. Oregon? And which side of the spread hits in 60 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.