The 24th-ranked San Diego State Aztecs (5-0) are set to square off against the San Jose State Spartans (3-3) on Friday night. The Aztecs are coming off an emphatic 31-7 victory over New Mexico in their last outing. The Spartans, meanwhile, suffered a 32-14 setback against Colorado State last week.  

Kickoff from CEFCU Stadium is set for 10:30 p.m. ET on CBS Sports Network. Caesars Sportsbook lists the Aztecs as 10-point road favorites, while the over-under, or total number of points Vegas thinks will be scored, is 41 in the latest San Diego State vs. San Jose State odds. Before locking in any San Jose State State vs. San Diego State picks, you need to check out the college football predictions from the SportsLine Projection model

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,800 for $100 players on its top-rated college football picks against the spread. It also enters Week 7 of the 2021 season on a 19-7 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has its sights set on San Diego State vs. San Jose State and released its picks and predictions. You can visit SportsLine now to see the model's CFB picks. Here are the college football odds and betting lines for San Jose State vs. San Diego State:

  • San Diego State vs. San Jose State: San Jose State -10
  • San Diego State vs. San Jose State over-under: 41 
  • San Diego State vs. San Jose State money line: San Diego State -400, San Jose State +310 
  • SDSU: The Aztecs are 7-1 straight up in their previous eight matchups against the Spartans 
  • SJSU: The Spartans are 8-1 straight up in their last nine home games
Featured Game | San Jose State Spartans vs. San Diego State Aztecs

Why San Diego State can cover

San Diego State features a lethal rushing attack. In fact, the Aztecs are averaging 244.4 rushing yards per game this season, the 11th-best mark in college football. In last week's victory over New Mexico, running back Greg Bell carried the ball 21 times for 111 yards and a touchdown. For the season, Bell has 94 carries for 520 yards and five touchdowns. 

San Diego State has also dominated this rivalry in recent years. The Aztecs have won seven of their last eight meetings against San Jose State, and they're a perfect 7-0 in their last seven games played in October. Plus, San Diego State is 4-1 against the spread in their last five games on the road against the Spartans. 

Why San Jose State can cover

The Aztecs have beaten the Spartans by more than 20 points four times since 2014, but San Jose State is starting to turn things around. SJSU secured an upset win over San Diego State last year, and this matchup has been decided by an average of 7.33 points over the previous three seasons. The Spartans can get the job done if they keep their hot streak at home going. 

San Jose State is 2-0 at home this year and has won its last three home games by an average of 18 points. While San Diego State is 1-0 on the road this year, the Aztecs ended 2020 with a three-game losing streak on the road. The Aztecs' quarterback carousel could benefit the Spartans. SDSU's Jordan Brookshire and Lucas Johnson are well below the national average in terms of completion percentage in 2021. If the Aztecs continue to rely heavily on their ground game, the Spartans could cover in a low-scoring contest.

How to make San Diego State vs. San Jose State picks

The model is leaning under on the point total and projects the teams to combine for 39 points. The model also says one side of the spread has all the value. You can only get the model's SDSU vs. SJSU pick at SportsLine.  

So who wins San Diego State vs. San Jose State? And which side of the spread has all the value? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that's entering Week 7 on a 19-7 roll on top-rated college football picks, and find out.