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The Vanderbilt Commodores will take on the Stanford Cardinal at 8 p.m. ET on Saturday at Vanderbilt Stadium. Vanderbilt is 1-1 after ending an 11-game losing streak vs. Colorado State last Saturday. Stanford pulled off an upset of No. 14 USC last week. Vanderbilt has not won a home game since Nov. 23, 2019. 

The Cardinal are favored by 12-points in the latest Vanderbilt vs. Stanford odds from Caesars Sportsbook, and the over-under is set at 48.5. Before entering any Stanford vs. Vanderbilt picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 3 of the 2021 season on a 67-50 run on all top-rated college football picks. Anyone who has followed it has seen huge returns..

Now, the model has set its sights on Vanderbilt vs. Stanford. You can head to SportsLine to see its picks. Here are several college football odds for Vanderbilt vs. Stanford:

  • Vanderbilt vs. Stanford spread: Vanderbilt +12
  • Vanderbilt vs. Stanford over-under: 48.5 points
Featured Game | Vanderbilt Commodores vs. Stanford Cardinal

What you need to know about Vanderbilt

Last Saturday, the Commodores narrowly escaped with a win over the Colorado State Rams 24-21. Joseph Bulovas hit the game-winning field goal with 19 seconds remaining. It was the first win for new head coach Clark Lea. Quarterback Ken Seals threw two touchdown passes and ran for another score. 

Vanderbilt overcame a 14-7 halftime deficit as the Rams missed two field goals and threw a third quarter interception. The Commodores were out-gained 305 to 120 in the first half. 

What you need to know about Stanford

Meanwhile, Stanford recorded a 42-28 upset victory over the USC Trojans last Saturday. Nathaniel Peat rushed for one TD and 115 yards on six carries. He ran for an 87-yard score. Tanner McKee passed for two TDs and 234 yards on 22 attempts and rushed for a TD in his first career start.  

Kyu Blu Kelly returned an interception 31 yards for a touchdown vs. USC. The Cardinal moved out to 21-10 lead before halftime on  Brycen Tremayne's TD catch. Stanford ended a nine-game regular season winning streak for USC.

How to make Stanford vs. Vanderbilt picks

The model has simulated Vanderbilt vs. Stanford 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Vanderbilt vs. Stanford? And which side of the spread hits more than 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks