The Ohio Bobcats will take on the Syracuse Orange at 7 p.m. ET on Saturday at Peden Stadium. Syracuse head coach Dino Babers knew the Ohio Bobcats well when Frank Solich was running the show after going head-to-head with him twice when he was at Bowling Green. Solich retired this offseason but long-time assistant Tim Albin is taking over, so Babers should know Ohio well schematically and Albin should be pretty familiar with what Babers wants to do.

The Bobcats haven't had a losing season since 2008 and Albin will be playing with house money in Saturday's opener, while Babers is coming in with an incredibly hot seat. The Orange are favored by one-point in the latest Syracuse vs. Ohio odds from Caesars Sportsbook, and the over-under is set at 56. Before entering any Ohio vs. Syracuse picks, you'll want to see the college football predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 1 of the 2021 season on a 57-37 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Ohio vs. Syracuse. You can head to SportsLine to see its picks. Here are several college football odds for Syracuse vs. Ohio:

  • Syracuse vs. Ohio spread: Syracuse -1
  • Syracuse vs. Ohio over-under: 56 points
Featured Game | Ohio Bobcats vs. Syracuse Orange

What to know about the Syracuse Orange

Coming off of an uninspired 1-10 record last season, Syracuse has set its aspirations higher this year. Syracuse was second worst in the nation when it came to yards per game last year, with the team coming up with only 265.3 on average but the Orange will hope that a year of continuity will help right their wrongs.

Babers' squad welcomes back 19 starters from last season and 80 percent of their overall production on both sides of the ball. Tommy DeVito is listed as the Week 1 starter but he'll be pushed by Mississippi State transfer Garrett Shrader. He played 10 games as a freshman before moving over and showed impressive athleticism, rushing for 587 yards and six touchdowns. He could provide a boost if DeVito continues to struggle the way that he did in 2020.

What to know about the Ohio Bobcats

The Bobcats only played three games a season ago but they managed a couple of wins and the rushing attack looked pretty formidable during that stretch. Albin will inherit most of the pieces from that rushing attack in his first season, with De'Montre Tuggle back after rushing for 403 yards and six touchdowns and running quarterback Armani Rogers.

Rogers and Kurtis Rourke were used in two very different roles in 2020 and could be deployed similarly in 2021. Rourke is the younger brother of Ohio legend Nathan Rourke and he's coming off a season where he averaged 8.8 yards per attempt. If Rourke can take a step forward as a passer, the Ohio offense should be well balanced.

How to make Syracuse vs. Ohio picks

The model has simulated Ohio vs. Syracuse 10,000 times and the results are in. We can tell you that the model is leaning under and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Syracuse vs. Ohio? And which side of the spread hits well over 60 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.