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Lane Kiffin returns to Neyland Stadium for the first time as an opposing head coach when the No. 13 Ole Miss Rebels (4-1) travel to take on the Tennessee Volunteers (4-2) on Saturday evening. Kiffin was Tennessee's head coach for one season in 2009 before bolting to USC that offseason. He's taken on Tennessee as the offensive coordinator at Alabama, but this is a matchup Tennessee fans have had circled on the calendar. 

Kickoff is set for 7:30 p.m. ET. The Rebels are one-point favorites, down two points from the opening line, in the latest Tennessee vs. Ole Miss odds from Caesars Sportsbook. The over-under is up to 82, the highest total of the week. Before making any Ole Miss vs. Tennessee picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,800 for $100 players on its top-rated college football picks against the spread. It also enters Week 7 of the 2021 season on a 19-7 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Tennessee vs. Ole Miss. You can head to SportsLine to see its picks. Here are several college football odds for Ole Miss vs. Tennessee:

  • Tennessee vs. Ole Miss spread: Ole Miss -1
  • Tennessee vs. Ole Miss over-under: 82 points
  • Tennessee vs. Ole Miss money line: Ole Miss -115, Tennessee -105
Featured Game | Tennessee Volunteers vs. Ole Miss Rebels

What you need to know about Tennessee

Like Ole Miss, Tennessee goes fast on offense and can pile up a ton of points. After a relatively uninspiring start to the Josh Heupel era in the first few weeks, the Vols have exploded for a combined 107 points in blowout wins against Missouri and South Carolina the past two weeks. Oddsmakers haven't been able to keep up as Tennessee easily covered in both matchup and those games went way over the total.

Virginia Tech transfer Hendon Hooker has settled in nicely as the starting quarterback after initially losing the starting job to Joe MIlton III to open the season. He's thrown for 1,063 yards, 13 touchdowns and just one interception. He's added 282 yards and three scores on the ground. An injury concern of note for the Vols is running back Tiyon Evans (ankle), who left last week's game early and could miss this matchup. 

What you need to know about Ole Miss

Meanwhile, it was all tied up 31-31 between Ole Miss and the Arkansas Razorbacks going into the fourth quarter last Saturday, but Ole Miss pulled a 52-51 victory out of their hat by stopping a 2-point conversion on the final play. Quarterback Matt Corral was a one-man wrecking crew for Ole Miss, passing for two touchdowns and 287 yards on 21 attempts in addition to rushing for two touchdowns and 94 yards.

Despite the loss to Alabama two weeks ago, Corral is still firmly entrenched in the Heisman Trophy campaign. The fourth-year junior is completing 69.2 percent of his passes and averaging 10.3 yards per pass attempt to throw for 1,497 yards and 12 scores without an interception. He's also rushed for 255 yards and eight scores and he'll be priority No. 1 for the Tennessee defense.

How to make Ole Miss vs. Tennessee picks

The model has simulated Tennessee vs. Ole Miss 10,000 times and the results are in. We can tell you that the model is leaning under and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Tennessee vs. Ole Miss? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its college football picks, and find out.