The 2020 SEC season begins on Saturday and the No. 16 Tennessee Volunteers will be on the road against the South Carolina Gamecocks. It's a 7:30 p.m. ET kickoff from Williams-Brice Stadium and around 20,000 fans will be permitted. Jarrett Guarantano will get the start for Tennessee at quarterback after helping lead the Volunteers to six consecutive wins to end the 2019 season. Tennessee has covered in six of its last eight games, while South Carolina has gone 1-5 against the spread in its last six, but the Gamecocks have won their last two against the Volunteers in Columbia.

The Volunteers are favored by four points in the latest South Carolina vs. Tennessee odds from William Hill. The over-under for total points is set at 44.5. Before entering any Tennessee vs. South Carolina picks, you'll want to see the college football predictions from the proven model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,800 for $100 players on its top-rated college football picks against the spread. It is a sizzling 13-1 on top-rated picks through three weeks of the 2020 college football season, returning over $900 in profit already. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on South Carolina vs. Tennessee. You can head to SportsLine to see its picks. Here are several college football odds for Tennessee vs. South Carolina:

  • South Carolina vs. Tennessee spread: Tennessee -4
  • South Carolina vs. Tennessee over-under: 44.5 points
  • South Carolina vs. Tennessee money line: South Carolina +150, Tennessee -170

What you need to know to about Tennessee 

Tennessee got off to a miserable 1-4 start where its only win was against FCS Chattanooga in 2019, but the Volunteers won seven of their last eight. That included wins as underdogs against Mississippi State, South Carolina, Missouri and Kentucky and a thrilling come-from-behind win over Indiana in the Gator Bowl.

The Tennessee defense was pretty dominant during that stretch, only allowing more than 5.0 yards per play in an October loss to Alabama. The Volunteers allowed just a 48.6 percent completion rate during their final seven wins of the season and they'll be a stiff test for a South Carolina offense that lost several key pieces from 2019. 

What you need to know about South Carolina 

The Gamecocks will turn to graduate transfer quarterback Collin Hill over incumbent Ryan Hilinski. Hill previously played at Colorado State and had an edge learning the offense since coordinator Mike Bobo used to be his head coach there. 

Will Muschamp's defense was competitive last year, giving up a respectable 26.1 points per game. South Carolina needs to build on that and find more consistency for an offense that ranked 104th nationally in scoring (22.4 ppg). The Gamecocks are replacing key players such as as receiver Bryan Edwards and running backs Rico Dowdle and Tavien Feaster on that side of the ball, so look for receiver Shi Smith and running backs Kevin Harris and Deshaun Fenwick to be bigger factors in 2020. 

How to make Tennessee vs. South Carolina picks

SportsLine's model has simulated South Carolina vs. Tennessee 10,000 times and the results are in. The model is leaning under on the total, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You can only see the pick at SportsLine.

So who wins Tennessee vs. South Carolina? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to see which side of the South Carolina vs. Tennessee spread to back, all from the advanced model that is up over $3,800 on its top-rated college football spread picks, and find out.