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The Texas Tech Red Raiders (6-4) host the No. 9 Oklahoma State Cowboys (9-1) in a Big 12 matchup at 8 p.m. ET on Saturday, Nov. 20 at Jones AT&T Stadium in Lubbock, Tex. Oklahoma State has won its last three games in blowout fashion after dropping a tight contest to Iowa State on October 23. Texas Tech is coming off an upset 41-38 win over Iowa State where kicker Jonathan Garibay nailed a walk-off 62-yard field goal. The Cowboys can get one step closer to locking up a spot in the Big 12 title game with a win. 

Oklahoma State is favored by 10.5 points in the latest Texas Tech vs. Oklahoma State odds from Caesars Sportsbook, and the over-under is set at 56.5. Before making any Oklahoma State vs. Texas Tech picks or CFB bets, you need to check out the college football predictions and betting advice from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It also enters Week 12 of the 2021 season on a 36-23 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Texas Tech vs. Oklahoma State and just released its coveted picks and college football predictions. You can head to SportsLine now to see the model's picks. Here are several college football odds for Texas Tech vs. Oklahoma State:

  • Texas Tech vs. Oklahoma State spread: Texas Tech +10.5
  • Texas Tech vs. Oklahoma State over-under: 56 points
  • Texas Tech vs. Oklahoma State moneyline: OSU -400, TTU +320

What you need to know about Texas Tech

The Iowa State Cyclones typically have all the answers at home, but on Saturday Texas Tech proved too difficult a challenge. Texas Tech narrowly escaped with a victory as the squad sidled past Iowa State 41-38. Texas Tech's win was all the more impressive since the Cyclones were averaging only 18.22 points allowed on the season. Texas Tech QB Donovan Smith was stellar, throwing for three TDs and 322 yards on 32 attempts in addition to picking up 50 yards on the ground.

The Red Raiders locked up bowl eligibility with their win last week, and have played a much more inspired brand of football since it was announced that Joey McGuire will be the program's next full-time head coach. TTU has battled inconsistency issues on both sides of the ball in 2021, which could be problematic against a team like Oklahoma State.

What you need to know about Oklahoma State

Meanwhile, the Cowboys turned the game against the TCU Horned Frogs into a track meet and took the gold after outgaining them 686 yards to 273. Oklahoma State claimed a resounding 63-17 victory over TCU at home. Their RB Jaylen Warren was dominant, rushing for three TDs and 113 yards on 17 carries.

The Cowboys control their own destiny in the Big 12, and are still in the think of the race for a spot in the College Football Playoff. Oklahoma State has been exceptional on the defensive side of the ball in 2021, giving up an average of 276.6 total yards and 16.4 points per game. Texas Tech has been inconsistent offensively, giving the Cowboys' defense a major advantage in this matchup.

How to make Oklahoma State vs. Texas Tech picks

The model has simulated Texas Tech vs. Oklahoma State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 60 percent of simulations. You can only see the model's Texas Tech vs. Oklahoma State pick at SportsLine.

So who wins Texas Tech vs. Oklahoma State? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to see which side of the Oklahoma State vs. Texas Tech spread you need to back, all from the model that has crushed its college football picks, and find out.