Paredes was placed on the 10-day injured list with a right shoulder strain Friday, Chandler Rome of the Houston Chronicle reports.
Paredes exited his relief appearance Thursday with the shoulder issue. Manager Dusty Baker had already deemed the right-hander unavailable for Friday's series opener against the Twins, but now Paredes is set for a longer absence. The Astros have yet to disclose a timetable for his return, but the reliever will be eligible to come off the IL on June 21. Ralph Garza was recalled in a corresponding roster move.