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With the meteoric rise of DFS, we are all becoming experts on splits. In our daily search for value, we may have gotten intimately acquainted with Ryan Raburn's viability against opposing lefties or Colby Lewis' affinity for pitching in Oakland. Those nuggets of information can be useful in daily Fantasy, but in leagues with weekly lineup deadlines, it requires the patience of waiting for just the right spot to use these otherwise Fantasy-irrelevant players when it's their time to shine.

The likes of Raburn and Lewis have little value for mixed league owners who set weekly lineups, but that doesn't mean that weekly players can't make use of players with extreme splits. In fact, knowing which players have put up lopsided splits can pay off with some of your borderline start/sit decisions.

Consider this your starter kit to extreme splits that are applicable to leagues with weekly lineups. I've hand-picked 11 players who deserve to be owned in standard mixed leagues, at the very least on a streaming basis, and are must-starts when the conditions are right. I'll also throw in a few enticing matchups for any player who is a speed threat.

Note: All stats are current for games played through Monday, April 27.

Mike Napoli, 1B, Red Sox

The pool of first basemen is always deep with productive bats, so it shouldn't be a surprise that Napoli -- with his .169/.280/.262 slash line -- is only owned in 49 percent of the leagues on CBSSports.com. Much of his production has come in the 20 plate appearances he has made against left-handed pitchers, which have produced his only home run and triple, as well as a pair of singles and six walks. Those numbers aren't too far out of line with the .923 OPS he has posted against southpaws going back to 2013. When the Red Sox have a weekly slate with three or four lefties, Napoli is worth starting, despite what his overall numbers might suggest.

Derek Norris, C, Padres

Like Napoli, Norris has done a disproportionate amount of his damage against lefties. That's actually an understatement, as he has batted .647 versus portsiders, as opposed to .224 against right-handed pitchers. Even after the inevitable regression occurs, Norris has a history against lefties that should inspire confidence. From 2013 to the present, Norris has posted a .960 OPS versus lefties, which has been bolstered by a .214 Isolated Power. In contrast, he has a very sittable .613 OPS and .094 Isolated Power against righties over the same period.

Charlie Blackmon, OF, Rockies

Few hitters are completely immune to the Coors Effect, but Blackmon has taken it to an extreme. In the last two-plus seasons, Blackmon has slashed .328/.380/.514 in Colorado and .257/.288/.381 on the road. Splits like that over an extended period should make your start/sit decision with Blackmon pretty easy.

Brian McCann, C, Yankees

It makes sense that McCann -- a left-handed flyball hitter -- would fare much better at Yankee Stadium than elsewhere, and that was clearly the pattern last season. McCann's .242 batting average at home was only 21 higher than his road mark, but he banged 19 of his 23 home runs in the Bronx. He's at it again in his second season with the Bombers; both of his homers have been at home, and he is batting .310 there as opposed to .194 in away games. McCann may be the seventh-ranked catcher in Fantasy points and Roto value, but he needs to be sat in mixed one-catcher leagues on road trips.

Daniel Murphy, 2B, Mets

While McCann is clearly a better play when in the Big Apple, Murphy may only be viable when he leaves it. From 2013 forward, Murphy has put up a .306/.341/.439 slash line in road games, but a .254/.298/.368 line at Citi Field. If you're hoping that the new, smaller dimensions will help Murphy this year in his home games, you may be disappointed. Murphy's downfall at home has been the largely the result of higher strikeout and popup rates. He hasn't done much on the road yet this season (.505 OPS), but his home performance (.653 OPS) is right in line with his recent history. With a .118 batting average on grounders, Murphy looks due for a correction, so he should be fine on the road going forward. His track record suggests that he needs to sit during home stands, though.

Wilson Ramos, C, Nationals

Ramos can't always be started, but the early-season schedule has presented owners with a buy-low opportunity. Nationals Park hasn't been hospitable to home run hitters, and Ramos has paid the price in hitting only nine of his 28 home runs since 2013 at his home park. He has one lone long ball so far in 2015, but 10 of the 16 games the Nationals have played have been in pitcher's parks. Many owners are averse to stashing a second catcher in a one-catcher league, but given how helpful Ramos can be in road games, he could be worth keeping around, despite his limitations.

Mark Trumbo, 1B/OF, Diamondbacks

If not for his home run power, Trumbo wouldn't have much Fantasy value, and because he is perennially among the major league leaders in average flyball distance, you might guess that Trumbo puts up his best numbers against flyball pitchers. That couldn't be further from the truth. Over the course of his career, Trumbo has batted .209 against flyball pitchers with a .172 Isolated Power, according to Baseball-Reference.com. Versus ground ball pitchers, those marks improve to .256 and .221, respectively. The staffs of the Giants, Dodgers and Padres currently rank among the top 10 in ground ball rate, so those intra-divisional opponents should provide Trumbo's owners with plenty of opportunities to start him. (Feel free to start him against the Rockies, too, despite their relative lack of ground ball pitchers.)

Curtis Granderson, OF, Mets

Granderson isn't quite as dependent on home run power for his Fantasy value as Trumbo is, but he has been much more of a flyball hitter. Fortunately for him, he has been far more productive against flyball pitchers than ground ball pitchers in recent seasons. He has yet to register an extra-base hit against a ground ball pitcher this year, and he hasn't slugged as high as .400 against ground ballers in either of the last two seasons. Monday night's 0-3 performance against ground ball specialist Jarred Cosart was no outlier, but NL East flyball pitchers like Dan Haren, Aaron Harang and even lefty Eric Stults can make an upcoming week look a lot more enticing.

C.J. Wilson, SP, Angels

Wilson has been better this season, but if you still have some doubts about whether he's worth starting, you can at least use him against lefty-heavy lineups. Over his career, Wilson has limited lefties to a .553 OPS, and even in his dismal 2014 season, that mark was a measly .572. In the AL West, the Mariners, Athletics and Rangers present good matchups, and in inter-divisional play, look for when Wilson faces the lefty-loaded Yankees and Indians.

Lance Lynn, SP, Cardinals

Lynn's overall stats -- especially those from last season -- give him the appearance of a must-start pitcher, but his career splits tell a different story. At pitcher-friendly Busch Stadium, Lynn has posted a 2.78 ERA, but on the road, that number spikes up to 4.13. He has simply been more homer-prone in his away starts, allowing 33 of his 47 home runs when he's not pitching in St. Louis. Even in 2014, Lynn allowed nine home runs in 88 2/3 away innings. He's a borderline option at best when pitching on the road.

Josh Collmenter, SP, Diamondbacks

Chase Field is no one's idea of a pitcher's park, so Collmenter just must like home cooking. He owns a career 3.19 home ERA as compared to a 3.76 ERA on the road. He's pitched with much better control at Chase Field (1.7 BB/9) than away from it (2.6 BB/9), and stronger popup tendencies at home have contributed to a .256 home BABIP over 315 2/3 innings.

And now, for some bonus information...Francisco Cervelli, Chris Iannetta and Kurt Suzuki are among this season's top five in most stolen bases allowed, and all three catchers have career caught stealing rates of 26 percent or lower. If your speedsters have a coming series against the Pirates, Angels or Twins, you need to get them in your lineup.