The Pirates designated Brice for assignment Wednesday.
Brice's stay in the majors lasted just five days, with the right-hander giving up an earned run while striking out three over three innings between his two relief appearances. He was moved off the 40-man roster and 26-man active roster to clear a spot for right-hander Roansy Contreras, who was recalled from Triple-A Indianapolis in advance of his scheduled start Wednesday versus the Red Sox.