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Santillan was optioned to Triple-A Louisville on Wednesday.

The 24-year-old gave up three runs (two earned) over three innings Tuesday and will head to the minors with Sonny Gray (groin) slated to rejoin the rotation this weekend. According to C. Trent Rosecrans of The Athletic, Santillan is expected to rejoin the Reds and work out of the bullpen after spending the required 10 days in the minors.

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