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The 2021 NFL Playoff Challenge featured eye-popping performances during Wild Card Weekend, including 145 scrimmage yards and a touchdown from running back Nick Chubb as the Browns upset the Steelers. Chubb will face a stern test in the Divisional Round of the 2021 NFL Playoffs as the Browns take on the No. 1-seeded Chiefs, but those who had Chubb in their NFL Playoff Challenge lineups last week will receive double points this week.

Running back Cam Akers had 176 scrimmage yards and a score in the Rams' win over the Seahawks last week and now will match up with the Packers. Can Akers put together another monster performance in the Divisional Round, and should he be among your NFL Playoff Challenge picks? Before setting any 2021 NFL Playoff Challenge lineups, be sure to see the picks and advice from SportsLine's Mike McClure, a DFS pro who has won almost $2 million. 

McClure uses a powerful prediction model that simulates every snap of NFL action in every game 10,000 times, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best values that he shares only with members at SportsLine.

He absolutely crushed his DFS picks during the the 2019 NFL regular season, finishing as high as the top 1 percent of tournaments on DraftKings and returning as much as 40x return in some higher-stakes tournaments. He then continued his roll in the postseason, cashing on every single lineup he posted for the divisional round. Anyone who has been following him has seen some huge returns. 

Now he's turned his attention to the 2021 NFL Playoff Challenge. Go here to see his full Divisional Round lineups

Top NFL Playoff Challenge picks for the 2021 Divisional Round

One of McClure's top NFL Playoff Challenge picks for the 2021 Divisional Round: Saints running back Alvin Kamara. After setting new career-highs for scrimmage yards (1,688) and total touchdowns (21) during the regular season, Kamara rushed for 99 yards and a score while adding two catches for 17 yards in the Saints' 21-9 win over the Bears in the Wild Card Round. 

Now, Kamara will take on a stout Buccaneers front, but his involvement in the passing game and targets in the red zone will help mitigate much of the risk. He was targeted 107 times during the regular season (second most among running backs), while his 57 red-zone touches were fourth-most in the NFL.

Kamara scored three times against Tampa Bay and had 10 catches on 14 targets in two games against them during the regular season.

How to build 2021 NFL Playoff Challenge lineups 

McClure is also targeting a pick that could go off for big numbers during the Divisional Round because of a dream matchup. This pick could be the difference between winning your NFL Playoff Challenge or going home with nothing. You can see who it is here.

So what is the optimal 2021 NFL Playoff Challenge lineups for the Divisional Round? Visit SportsLine now to see the full optimal tournament lineups for the NFL Playoff Challenge this weekend from a professional DFS player who has almost $2 million in career winnings, and find out.