The 49ers placed Aiyuk on the reserve/ COVID-19 list Wednesday, Mike Garafolo of NFL Network reports.

The hits keep coming for the 49ers, who placed Kendrick Bourne on the COVID-19 list earlier Wednesday due to a positive test result. Aiyuk and Deebo Samuel (hamstring) have been deemed to be high-risk close contacts of Bourne, meaning they'll be sidelined Thursday against the Packers. With that trio sidelined, San Francisco may be down to just two available wide receivers -- Trent Taylor and Richie James -- in Week 9, but the latter player is questionable to play himself due to an ankle injury.

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