Hightower (knee) was held out of action in Friday's preseason opener against Kansas City, Matt Maiocco of NBC Sports Bay Area reports.

The veteran running back has been dealing with a minor knee injury and it was bothering him enough to keep him sidelined for Week 1 of the preseason. The 49ers haven't provided specifics in regard to the severity of the injury, but Hightower's participation in practice this upcoming week should give us a better idea as to when he's expected to make his debut in red and gold. The 31-year-old is currently listed as the primary backup to Carlos Hyde, but he will have to fend of rookie Joe Williams for touches as the regular season approaches.

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