The Cardinals placed Jefferson (knee) on injured reserve Tuesday, Josh Weinfuss of ESPN.com reports.

Jefferson has been diagnosed with a Grade 2 MCL sprain, which will officially bring his breakout season to a close. Although he didn't record a tackle before departing Saturday's game in Seattle, he'll finish his fourth campaign with a career-high 96 tackles (78 solo), to which he tacked on five passes defended, two sacks, two forced fumbles, and two fumble recoveries. Expect Jefferson to be a hot commodity as an unrestricted free agent in the offseason.

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