Jackson had ankle surgery Tuesday and is expected to be out for two-to-four weeks, Lindsey Thiry of ESPN.com reports.
With the surgery occurring 19 days before the Chargers' regular season opener, Jackson seems more likely to miss the game than play in it. A Thursday game in Week 2 is suboptimal as well in terms of avoiding multiple absences, but at this point the Chargers haven't completely ruled him out for even Week 1. Jackson signed a five-year, $82.5 million contract in the offseason and now teams up with safety Derwin James and edge rushers Joey Bosa and Khalil Mack to give the Chargers a star-studded defense. They'll need to live up to their reputations, facing Derek Carr and the Raiders in their season opener before traveling to Kansas City for a date with Patrick Mahomes on a short week.