Smith (undisclosed) was placed on the reserve/COVID-19 list Monday.
Smith joins starting guards Mark Glowinski and Quenton Nelson in COVID protocols. With starting left tackle, Eric Fisher suffering a knee injury Sunday against the Cardinals and Ryan Kelly absent due to personal reasons, the entire Colts offensive line's availability for Week 17 against the Raiders is up in the air. If Smith is vaccinated, he'll need to produce two negative tests more than 24 hours apart to clear protocols.