NFL training camps are opening, and 2021 Fantasy football rankings are taking shape. Smart owners have already begun their 2021 Fantasy football draft prep, but strategies will have to be adjusted on the fly as injury news comes in. Rams running back Cam Akers ruptured his Achilles last week, and now Darrell Henderson is rising quickly in the 2021 Fantasy football running back rankings as the new No. 1 running back for Sean McVay.

Where should you target Henderson with your 2021 Fantasy football picks, and who are some of the 2021 Fantasy football sleepers, breakouts and busts you need to be aware of? A reliable set of Fantasy football rankings 2021 can help you answer those questions and also ensure you get maximum value out of every pick. Before setting your 2021 Fantasy football draft strategy, be sure to check out the 2021 Fantasy football cheat sheets from the proven computer model at SportsLine.

Last year, the model accurately predicted that Bills quarterback Josh Allen was being drastically undervalued. His Fantasy football ADP was barely in the top 70, but the model pegged him as a top-five Fantasy quarterback, a QB1 who would finish well ahead of players like Kyler Murray, Tom Brady and Drew Brees. Allen ended up being the No. 2-scoring Fantasy QB, outscoring all three of those other quarterbacks and even surpassing Patrick Mahomes. Fantasy players who followed SportsLine's advice reaped plenty of value with that pick. 

The same model has a proven track record providing Fantasy football tips, also identifying A.J. Brown as another sleeper in 2020 and players like Devin Singletary and JuJu Smith-Schuster as busts last season. Additionally, it's called past Fantasy football sleepers like Derrick Henry in 2019, Christian McCaffrey and Alvin Kamara in 2018, and Davante Adams in 2017. Anybody who banked on players like those made a run at their league title.

The model is powered by the same people who generated projections for all three major Fantasy sites, and it beat human experts last season when there was a big difference in ranking. The projections update multiple times daily, so you're always getting the best Fantasy football advice.

Now, SportsLine has simulated the entire NFL season 10,000 times and released its latest Fantasy football rankings 2021, along with plenty of sleepers, breakouts and busts. Head to SportsLine now to see them

Top 2021 Fantasy football sleepers 

One of the 2021 Fantasy football sleepers the model is predicting: Dolphins wide receiver DeVante Parker. The former first-round pick finally broke out in 2019 after four mediocre seasons to begin his career, catching 72 passes for 1,202 yards and nine touchdowns. However, Parker missed multiple games last season and saw his overall productivity drop off.

Parker still had a respectable 63 catches for 793 yards and four touchdowns, but Miami's passing offense as a whole ranked just 20th in the NFL in passing yards and 22nd in passing touchdowns. Will Fuller and Jaylen Waddle stand to enhance the passing attack, and quarterback Tua Tagovailoa should take a step forward in his second season. That's a big reason why the model likes Parker (13th round 2021 Fantasy football ADP) ahead of 10th-round options like Curtis Samuel and DeVonta Smith.

Top 2021 Fantasy football breakouts 

The model is also projecting Patriots running back Damien Harris as one of its top 2021 Fantasy Football breakouts. The third-year pro rushed for 691 yards on 137 carries and two touchdowns in 2020 despite playing in just 10 games. Harris missed time in 2020 due to back and ankle injuries.

Despite his abbreviated sophomore campaign, Harris clearly seized the RB1 spot in New England away from Sony Michel. The former Alabama standout has a strong chance to get close to a 1,000-yard season in 2021 if he can remain healthy, as his 5.0 yards-per-carry average is a respectable clip. SportsLine's 2021 Fantasy football running back rankings agree, listing Harris ahead of backs like Javonte Williams, Michael Carter and Trey Sermon.

Top 2021 Fantasy football busts

As for players to avoid, the model lists Eagles wide receiver DeVonta Smith as one of its top 2021 Fantasy football busts. The 2020 Heisman winner was the 10th overall draft pick after a record-breaking season at Alabama. Smith averaged over 142 receiving yards per game while also scoring 25 total touchdowns across 13 contests.

While Smith reunites with former Crimson Tide quarterback Jalen Hurts, his most productive seasons in Tuscaloosa came when different Alabama quarterbacks were throwing him the ball. His Heisman season came with Mac Jones, while his 1,256-yard 2019 season came with Tua Tagovailoa. Hurts' limitations as a passer prevented Smith from reaching his full potential in college and he brought many of those limitations with him to Philadelphia.

The Eagles have also devoted much of their offseason to amplifying their backfield, as the team projects to be run-heavy in 2021. Smith has an eighth-round 2021 Fantasy football ADP, but the SportsLine model sees him as being on par with receivers like Tyrell Williams and Laviska Shenault, both of whom are being drafted in the 10th round or later.

How to find proven 2021 Fantasy football football rankings

SportsLine is also extremely high on a surprising quarterback you aren't even thinking about being drafted in the middle rounds of 2021 Fantasy football drafts. This quarterback is listed as a shocking top-five option ahead of superstars like Patrick Mahomes and Lamar JacksonYou can only see who it is, and the 2020 Fantasy football rankings for every player, at SportsLine.

So which 2021 Fantasy Football sleepers, breakouts and busts should you target and fade? And which QB shocks the NFL with a top-five performance? Visit SportsLine now to get 2021 Fantasy Football cheat sheets for every single position, all from the model that called Josh Allen's huge season, and find out.