It's been a tough week for receivers heading into Week 4 with Josh Gordon deciding to enter rehab and significant injuries to Dez Bryant (knee) and Eric Decker (shoulder). On Friday, we had more bad news with the Bills placing Sammy Watkins on injured reserve because of continued problems with his surgically-repaired foot.

And now it's time for Fantasy owners to cut Watkins in the majority of leagues.

Sammy Watkins
BAL • WR • 14
2016 stats
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There are obvious exceptions to hold onto Watkins in keeper and dynasty formats, and if your league has an IR spot, you can stash him. Watkins can still come back in eight weeks if the Bills opt to use their one designated return spot for him, but he also might not play again this year.

He only appeared in two games this season and had six catches for 63 yards, and hopefully that's not the lasting impression we'll have of Watkins, who had a third-round Average Draft Position on CBS Sports. But Fantasy owners need to move on with their rosters, and hopefully there are options on your waiver wire (more on that below).

The Bills will now go with Robert Woods and Marquise Goodwin as their top receivers, and neither are inspiring as Fantasy options. Woods is the preferred choice in deeper leagues, and Buffalo also signed Justin Hunter for depth.

This is clearly bad news for Tyrod Taylor, who should be considered a No. 2 Fantasy quarterback moving forward, and it will be hard to trust him as a starter in most standard formats. LeSean McCoy should remain a No. 1 Fantasy running back, but teams are clearly going to load up the line of scrimmage to stop him with the lack of weapons on offense. Still, based on his talent level, he should produce quality stats more often than not.

The main thing for Fantasy owners is how to replace Watkins, and here are some of the receivers we would consider adding if they are available. This could also be useful if you just lost Gordon, Bryant and Decker this week. We'll use our usual waiver wire format of 65 percent ownership or less in CBS Sports leagues.

  • Quincy Enunwa (56 percent): With Decker out, he should get a bump in production moving forward.
  • Kevin White (50 percent): He had 14 targets in Week 3 at Dallas and could be ready to take off.
  • Jamison Crowder (49 percent): He leads WAS in targets (25), catches (16) and receiving TDs (2).
  • Steve Smith (54 percent): He just had his best game in Week 3 with eight catches for 87 yards.
  • Cole Beasley (60 percent): Bryant's injury could mean more targets for this PPR sleeper.
  • Chris Hogan (39 percent): His time is coming once Tom Brady is back in Week 5.
  • Kenny Stills (19 percent): His big-play ability was on full display Thursday night at Cincinnati.
  • Robert Woods (7 percent): The new No. 1 in Buffalo, he should get plenty of targets from Taylor.
  • Corey Coleman (49 percent): A stash candidate, he could be good once he's back from his hand injury.
  • Anquan Boldin (28 percent): He's scored in two consecutive games for the Lions.
  • Adam Humphries (14 percent): He has 15 catches for 167 yards in his past two games.

None of these guys will produce like Watkins -- or Gordon, Bryant or Decker either. And it's not fun to lose players you drafted in the first three rounds (just ask the Adrian Peterson and Keenan Allen owners).

But we have to move on and do the best thing for our Fantasy rosters. And hopefully there are receivers available off waivers to help you remain competitive in your leagues.