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Williams will replace Rashad Jennings for the Giants, who is dealing with a sprained left MCL and could be out until Week 9, according to reports. Hillman is expected to start for the Broncos in place of Montee Ball, who could miss at least two weeks with a groin injury. And Oliver could start for the Chargers this week if Donald Brown (concussion) is out and Ryan Mathews (knee) is still not ready to return.
All three replacement running backs could be considered starting Fantasy options in Week 6, but the key is deciding which one you want the most off waivers and how much it could cost you in bid points. I'll be going after Williams first, Oliver second and then Hillman.
The reason I like Williams (56 percent ownership on CBSSports.com) the best is he should be starting this week at Philadelphia and Week 7 at Dallas, which are two good matchups, and then New York has a bye in Week 8. He'll get all the work, and the Giants offense is starting to click. Williams also has a touchdown in consecutive games with 131 rushing yards over that span.
Oliver (13 percent) would be next, and I love his outlook for Week 6 at Oakland. But there's still the uncertainty of Brown playing this week, and Mathews could return as early as Week 7. Oliver doesn't have the potential staying power of Williams, although he could be a great one-week starter against the Raiders. Oliver just had 19 carries for 114 yards and a touchdown and four catches for 68 yards and a touchdown against the Jets.
Hillman (11 percent) could get an extended look with Ball out, but his matchups are daunting over the next few weeks against the Jets, 49ers, Chargers and Patriots. Hillman also could be splitting time with C.J. Anderson and Juwan Thompson, which could limit is upside. But Hillman ran well against the Cardinals when Ball went down in Week 5 with 15 carries for 64 yards. If he does well with Ball out, he could make a case for more playing time.
Injuries: Jake Locker (hand), Drew Stanton (concussion), Carson Palmer
(shoulder), Teddy Bridgewater (ankle), Derek Carr (knee), Robert Griffin III
(ankle), Josh McCown (thumb)
Key players on bye: Drew Brees, Alex Smith
Priority list (add them in this order): Austin Davis (9 percent ownership), Carson Palmer (65 percent), Ryan Tannehill (43 percent), Mike Glennon (15 percent), Teddy Bridgewater (35 percent), Brian Hoyer (8 percent), Zach Mettenberger (1 percent), Michael Vick (7 percent) and Kyle Orton (8 percent)
Potential drop candidates: Joe Flacco (75 percent), Alex Smith (63 percent), Jake Locker (20 percent)
Why Davis is the best: It's not a good week for quarterbacks, and I expect Davis to be the best of this waiver wire group in Week 6. I'd take Palmer first if he was guaranteed to play against the Redskins, and the hope is he can return soon, making him the best long-term solution. But Davis has done a nice job in comeback-type efforts the past two games against Dallas and Philadelphia with a combined 59 Fantasy points on 701 passing yards, six touchdowns and two interceptions. It won't be pretty against the 49ers, but he could be throwing a lot, hopefully to Quick.
Of note: As I said, if Palmer is healthy this week he should be added in all leagues and potentially started with his matchup against the Redskins. We hope to get good news on Palmer by Wednesday after he's missed the past three games. ... Tannehill, Glennon and Bridgewater are all kind of the same because they'll have inconsistent performances, with Bridgewater the best long term. I like Tannehill throwing this week against the Packers, and the Dolphins are getting healthy with Mike Pouncey (hip) expected to play and Knowshon Moreno (elbow) potentially back. ... Glennon has made two starts the past two games, and he's scored at least 19 Fantasy points in both outings against Pittsburgh and New Orleans. He has a tough matchup against Baltimore, but you can almost pencil him in for around 18 or 19 Fantasy points, especially with a non-existent running game. ... Bridgewater is expected to return this week against the Lions after being out in Week 5 with an ankle injury. In his first start against the Falcons in Week 4 he was solid with 22 Fantasy points, and we hope that's an indication of what he's capable of. But I don't like the matchup against the Lions, which is why he's behind Tannehill and Glennon this week as a bye-week replacement. ... Hoyer has done a nice job this year with minimal weapons to keep his job and leave Johnny Manziel on the bench. He had his best performance in Week 5 at Tennessee with 27 Fantasy points in that tremendous comeback effort, and he could score at least 17 points this week against the Steelers. I wouldn't rule him out in deeper leagues as a bye-week replacement. ... You can start speculating on Mettenberger and Vick now because they could be starting soon for their respective teams in Tennessee and New York. The Titans can't count on Locker staying healthy, and they might want to see if Mettenberger is a future starter. And Geno Smith is barely holding onto his starting job. Even though Vick wasn't good in replacing Smith in Week 5 at San Diego, he might give the Jets a better chance to win, which could help save Rex Ryan's job.
Injuries: Montee Ball (groin), Donald Brown (concussion), Reggie Bush
(ankle), Rashad Jennings (knee), Zac Stacy (calf), Fred Jackson
(ankle), Joique Bell (concussion), DeAngelo Williams (ankle), Ryan Mathews
(knee), Knowshon Moreno (elbow), Mark Ingram (hand), Jonathan Stewart
(knee), Mike Tolbert (leg)
Key players on bye: Jamaal Charles, Knile Davis, Khiry Robinson and Pierre Thomas
Priority list (add them in this order): Andre Williams (56 percent ownership), Branden Oliver (13 percent), Ronnie Hillman (11 percent), Benny Cunningham (15 percent), Antone Smith (12 percent), Bobby Rainey (56 percent), Storm Johnson (1 percent), C.J. Anderson (7 percent), Theo Riddick (1 percent), Chris Ogbonnaya (5 percent), George Winn (0 percent), Juwan Thompson (0 percent)
Potential drop candidates: Adrian Peterson (89 percent), Chris Johnson (87 percent), Donald Brown (78 percent), Toby Gerhart (76 percent), Terrance West (75 percent)
Why Williams is the best: As stated above, he has the best chance to start and be featured for the next two games with Jennings out. He had 15 carries for 66 yards and a touchdown in Week 4 at Washington and 20 carries for 65 yards and a touchdown and two catches for 18 yards against Atlanta in Week 5 when Jennings got hurt. He should do well this week against the Eagles, who have allowed a running back to score in each of their past four games. And since Jennings has a long injury history, we might see Williams get plenty of chances to start as the season goes on.
Of note: After Jennings, I would add Oliver and then Hillman. Oliver could be the featured option against the Raiders this week, and Hillman could start for the Broncos for the next two or three games with Ball out. ... The hope is Hillman will get the majority of work for the Broncos, but you should expect a committee approach with Anderson and Thompson also seeing action. If I miss on Hillman, I'd add Anderson first and then Thompson in deeper leagues. ... Once you get past the top three guys at the position to add this week, Cunningham should be considered the No. 4 priority. Stacy is expected to play Monday night against the 49ers, but he left Week 5 with a calf injury. Cunningham played well in his place against the Eagles with seven carries for 47 yards and a touchdown and three catches for 24 yards. He'd be a low-end starting option if he started for Stacy against San Francisco. ... All Smith does is score big touchdowns for the Falcons, who need to start giving him more work. He doesn't have more than four touches in any game this season, but he's scored on runs of 38 and 48 yards and receptions of 54 and 83 yards in four of five games. He's worth a speculative add in case the Falcons would feature him should Steven Jackson get hurt. ... The Buccaneers may start giving Rainey more work again with Doug Martin struggling. Rainey only had nine touches at New Orleans in Week 5, but he scored a touchdown. This running game needs a spark from someone. ... Speaking of bad running games, the Jaguars may turn to Johnson this week with Toby Gerhart quickly falling out of favor. Johnson made his NFL debut in Week 5 against Pittsburgh and had four carries for 27 yards. They need help in that backfield, and I would add Johnson in deeper leagues. ... Riddick is worth a look in deeper leagues if he's able to return from his hamstring injury this week. He could help replace Bush, who is expected to sit in Week 6 at Minnesota. Winn could also get an extended look, but Bell is expected to play against the Vikings after being out with a concussion.
Injuries: Calvin Johnson (ankle), Eric Decker (hamstring), Malcom Floyd
(calf), Mike Evans (groin), Cecil Shorts (hamstring), Rod Streater
(foot), Marvin Jones (foot), Marqise Lee (hamstring), Jarrett Boykin
(groin), Donnie Avery (groin)
Key players on bye: Marques Colston, Brandin Cooks, Dwayne Bowe
Priority list (add them in this order): Brian Quick (65 percent ownership), Odell Beckham (20 percent), Justin Hunter (36 percent), Mohamed Sanu (44 percent), Allen Robinson (41 percent), Devin Hester (18 percent), Davante Adams (9 percent), Kenny Britt (10 percent), Riley Cooper (47 percent), Louis Murphy (5 percent), Travis Benjamin (0 percent), Taylor Gabriel (0 percent)
Potential drop candidates: Torrey Smith (83 percent), Dwayne Bowe (70 percent), Hakeem Nicks (61 percent), Mike Evans (58 percent), Greg Jennings (53 percent)
Why Quick is the best: He's a guy we've been talking about in this space for quite some time now, and I hope he's 100 percent owned by Sunday. He's scored at least seven Fantasy points in all four games this season in a standard league and at least 14 points in PPR. He has nine targets in three of four outings, and he's scored three touchdowns in his past two games, with two coming in Week 5 at the Eagles. He's easily the best receiver and likely the best weapon for the Rams, and Davis is leaning on him. He should be no worse than a No. 3 receiver moving forward with the chance to start based on his performance through the first four games of the season.
Of note: If Kendall Wright (78 percent) and Rueben Randle (76 percent) are still available in your leagues, add them after Quick, with Randle at the No. 2 spot. ... Beckham did well in his NFL debut with four catches for 44 yards and a touchdown on five targets against the Falcons. He will still remain the No. 4 option in the passing game behind Victor Cruz, Randle and Larry Donnell, but he could turn into a nice weapon for the Giants. His performances will likely be inconsistent as a rookie, but he could have some big games down the road. ... Hunter finally had a big game in Week 5 against the Browns with three catches for 99 yards and a touchdown, and he started over Nate Washington for the first time this season. We wish the Titans had a better quarterback situation, but maybe Mettenberger can help maximize Hunter's talent. I'd speculate on Hunter if you have an open roster spot. ... Sanu has done a nice job of producing quality stat lines for Fantasy owners. He had five catches for 90 yards and a touchdown in Week 5 at New England and has now scored in double digits in Fantasy points in three games in a row. He could lose some production once Jones returns, but I'd look at him as a No. 3 receiver in deeper leagues. The encouraging news is Sanu had 17 targets the past two games against Tennessee and New England. ... Robinson is due for a big game. He had five catches for 51 yards on 11 targets against the Steelers, and he has at least five catches in each of the past three games with 28 targets over that span. He's a nice stash candidate in PPR leagues, and he's a sleeper in Week 6 at Tennessee. ... I like Hester as a deep sleeper this week at home against his former team, especially if Douglas remains out. ... There aren't a lot of starting options in the rest of the receiver group, but I'd speculate on Adams in deeper leagues as the No. 3 receiver for the Packers with Boykin hurt. ... Benjamin scored two touchdowns at the Titans, but he hasn't had more than four targets in any game this year, so consider his performance in Week 5 fluky.
Injuries: Jimmy Graham
(shoulder), Vernon Davis (back), Jordan Reed (hamstring), Joseph Fauria
(ankle), Tyler Eifert (elbow) and Kyle Rudolph (groin)
Key players on bye: Jimmy Graham, Travis Kelce
Priority list (add them in this order): Dwayne Allen (72 percent ownership), Timothy Wright (8 percent), Owen Daniels (59 percent), Jordan Reed (62 percent), Eric Ebron (37 percent), Kyle Rudolph (42 percent), Ladarius Green (36 percent), Luke Willson (9 percent)
Potential drop candidates: Niles Paul (58 percent), Charles Clay (40 percent), Coby Fleener (35 percent)
Why Allen is the best: If Allen is owned in too many leagues then add Wright, but Allen has staying power for the rest of the year. He has a touchdown in four of five games, and he should be the best red-zone target for the Colts this season. He has five red-zone targets on the year, and he's finished with five catches for 27 yards and three touchdowns. I'd rather have Allen than Jordan Cameron, Jason Witten and Zach Ertz for the rest of the season.
Of note: Even though Wright played just 19 snaps against the Bengals in Week 5, it was clear the Patriots wanted to get him going. He had a season-high five targets, and he finished with five catches for 85 yards and a touchdown. We hope this is a sign of things to come because the Patriots need another weapon in the passing game, and we'd speculate on Wright in all formats. ... Daniels isn't going to be as good as Dennis Pitta (hip) might have been if he stayed healthy, but he had five catches for 70 yards at the Colts in Week 5 and has 13 targets in two starts since Pitta went down. He's a safe option and should do well against Tampa Bay this week. ... I'd look at Reed and Rudolph now with their impending returns from injury. Reed could play in Week 6 at the Cardinals, which would be a great matchup, and he should replace Paul as the starter. And Rudolph could be back in a couple of weeks with the hope he still has a breakout season in Norv Turner's offense. ... Ebron is a nice sleeper in Week 6 with Calvin Johnson hurt, and he had a touchdown called back in Week 5 at Buffalo when he was ruled down at the 1-yard line. He should see more than the four targets he's had in each of the past two games with the Lions needing to replace Johnson's production. ... Green is worth a speculative add with Floyd hurt. He had a touchdown negated by a penalty in Week 5 against the Jets, but he could see more action to help replace Floyd. ... Willson is a pure gamble play in deeper leagues against the Cowboys since they have struggled to defend tight ends all season.
Ravens: 59 percent
Colts: 44 percent
Giants: 22 percent