Witherspoon (hamstring) has been ruled out for Sunday's matchup against the Bengals, Teresa Varley of the Steelers' official site reports.
Witherspoon is slated to miss a second straight contest due to a lingering hamstring injury that's cost him a total of six games this season. Levi Wallace will likely continue operating as the starting cornerback opposite Cameron Sutton while Arthur Maulet sees work in nickel and dime packages.