Mabin (ankle) has been ruled out of Sunday's game against the Texans, according to Jim Wyatt of the Titans' official site.
Mabin has played in just two games this season and hasn't seen the field since Week 8, when he featured in 80 percent of the snaps during a 34-31 win over the Colts. Mabin will now miss a third straight game, and his next chance to feature will come Oct. 28 on the road against the Patriots.